Results 231 to 240 of about 25,642 (304)

Surgical Repair of Supracristal Ventricular Septal Defect With Combined Multivalvular Disease in an Elderly Patient: A Transaortic Approach. [PDF]

Interdiscip Cardiovasc Thorac Surg
Kanemitsu S, Maruyama S, Yamasaki T, Kajiyama K.   +3 more
europepmc   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

CT-based visualization of aortic valve morphology: from 3D energy-integrating CT to 4D photon counting CT. [PDF]

Front Cardiovasc Med
Pouch AM, Dong JN, Litt HI, Cannon BJ, Freas M, Ferrari V, Gleason TG, Jolley MA, Yushkevich N, Nunez J, Hao J, Guo Z, Goldfinger S, Kelly J, Bavaria JE, Desai ND.   +15 more
europepmc   +1 more source

A Fentanyl‐Responsive Microneedle Patch for Harm Reduction

Advanced Science, EarlyView.
A fentanyl‐responsive microneedle patch is developed as a self‐regulating overdose intervention that releases naloxone upon detecting fentanyl. The system employs aptamer‐functionalized nanoparticles embedded in a swellable polymer matrix to enable rapid, on‐demand drug delivery through the skin.
Penghui Zhao, Zerui Zhou, Tyler Wolter, Huanqing Niu, Yuanzhi Bian, Chixia Tian, Chun Xu, Chenming Zhang, Juhong Chen, Matthew W. Buczynski, Wujin Sun   +10 more
wiley   +1 more source

Rare Coexistence of a Single Coronary Artery, Myocardial Bridging, and Bicuspid Aortic Valve Detected by Coronary Computed Tomography Angiography During Preoperative Assessment: A Case Report and Literature Review. [PDF]

Reports (MDPI)
Machowiec P, Przybylski P, Czekajska-Chehab E.   +2 more
europepmc   +1 more source

High‐Throughput Screening and Interpretable Machine Learning for Rational Design of Bimetallic Catalysts for Methane Activation

Advanced Science, EarlyView.
ABSTRACT Methane's efficient catalytic removal is vital for sustainable development. Bimetallic catalysts, though promising for methane activation, pose a design challenge due to their complex compositional space. This work introduces an integrated framework that combines high‐throughput density functional theory (DFT) and interpretable machine ...
Mingzhang Pan, Tian Zhang, Jiawei Dong, Yubao Xie, Kaifeng Zhong, Wei Guan, Haiqiao Wei, Changcheng Fu, Yaqiong Su   +8 more
wiley   +1 more source

Acute Stanford Type A Aortic Dissection After Transcatheter Aortic Valve Implantation Necessitating the Bentall Procedure: A Case Report. [PDF]

Cureus
Yokoyama N, Miyoshi K, Shinoda D, Shiraishi M.   +3 more
europepmc   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

Rare Coexistence of Uncommon Congenital Valve Duo in an Adult: Double Orifice Mitral Valve and Bicuspid Aortic Valve. [PDF]

CASE (Phila)
Rasheed S, Zahra K, Fatima M, Rehman W, Aarij KM, Khail SK, Akhtar P.   +6 more
europepmc   +1 more source