Results 61 to 70 of about 25,642 (304)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Observations of nonlinear run-up patterns on plane and rhythmic beach morphology

open access: yes, 2010
Application of non-linear forecasting and bispectral analysis to video observations of run-up over cuspate topography shows that these alongshore patterns in the morphology are accompanied by changes to the fundamental behaviour of the run-up timeseries.
Coco, Giovanni   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Cusps are Dense [PDF]

open access: yes, 2010
We show cusps are dense in Bers' boundary for Teichmuller space. The proof rests on an estimate for the algebraic effect of a unit quasiconformal deformation supported in the thin part of the Riemann surface.MathematicsVersion of ...
McMullen, Curtis
core   +1 more source

Successful ablation of a left anterior accessory pathway from the left coronary sinus of Valsalva near the aortic–mitral continuity

open access: yesJournal of International Medical Research, 2021
Catheter ablation of accessory pathways can be challenging depending on the location of these pathways, and accessory pathways are rare through the aortic cusps.
Fan Wang   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Prevalence of talon cusps in a Portuguese population: Forensic identification significance of a rare trait

open access: yesDental Research Journal, 2014
Background: Dental techniques are frequently used in human identification; some of those include comparative analyses of dental features that, being rare or unique to an individual, can establish a positive identification.
Ricardo Jorge Simões   +2 more
doaj   +1 more source

Cusp summations and cusp relations of simple quad lenses [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2015
We review five often used quad lens models, each of which has analytical solutions and can produce four images at most. Each lens model has two parameters, including one that describes the intensity of non-dimensional mass density, and the other one that describes the deviation from the circular lens. In our recent work, we have found that the cusp and
Chu, Zhe, Li, G. L., Lin, W. P.
openaire   +2 more sources

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