Results 31 to 40 of about 7,679 (266)

Permohonan Tanah Ulayat di Minangkabau Menjadi Tanah Hak Milik

Lentera Hukum, 2018
Communal land is an asset owned by customary law communities and jointly managed by members of customary law communities. Customary land in Minangkabau has been recognized in Indonesian law and mentioned in Article 3 of the Basic Agrarian Law Number 5 of
Siti Raga Fatmi
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Gongqose v Minister of Agriculture, Forestry and Fisheries – A Tale of Customary Rituals and Practices in Marine Protected Areas

Potchefstroom Electronic Law Journal, 2019
The correct application of customary law post constitutionalism continues to be the subject of much judicial and academic deliberation. This is especially true where the existence and/or scope of customary rights and cultural practices are not well ...
Lesetja Monyamane, Mpho Paulos Bapela
doaj   +1 more source

Pengakuan Kedudukan Hukum Masyarakat Hukum Adat Matteko dalam Pengujian Undang-Undang di Mahkamah Konstitusi

Jurnal Konstitusi, 2022
The constitution states that as long as the customary law community unit and its traditional rights are still alive and in accordance with the development of society and the principles of the unitary state of the Republic of Indonesia, the state ...
Andi Melantik Rompegading, Maemanah Maemanah   +1 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Baduy Customary Law from the Perspective of Human Rights and Religious Freedom

SASI
Baduy customary law is a system of norms that governs the social, spiritual, and ecological life of the Baduy people in Banten. The uniqueness of this customary law lies in its adherence to the principle of pikukuh karuhun (ancestral rules), which ...
Zaenudin Zaenudin, Eli Apud Saepudin
doaj   +1 more source

Pembuktian Kepemilikan Tanah Adat Minahasa Pasini Dalam Praktik Penyelesaian Sengketa Tanah Di Sulawesi Utara

Jurnal Nuansa Akademik, 2023
The aim of the research is to find out the use of Pasini land by the Minahasa people. Pasini land ownership proof system in the settlement of land disputes in court at this time. By using normative legal research methods supported by empirical studies as
Jemmy Sondakh, Eugenius Paransi, Cevonie Marietje Ngantung   +2 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Customary Rights: Holding the Line

Public History Review, 2006
This article explores the nature, history and significance of Maori customary rights in the New Zealand context, and argues there is a need for a New Zealand constitution which embodies human rights which recognise and uphold the customary rights of the indigenous peoples of this land and protects those rights from oppressive and discriminatory ...
openaire   +5 more sources