Results 51 to 60 of about 868,959 (309)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Establishment of event-specific quantitative real-time polymerase chain reaction for detecting genetically modified sugarbeet GTSB77

open access: yesZhongguo shipin weisheng zazhi, 2020
Objective For implementation of labeling regulations, an event-specific real-time polymerase chain reaction (PCR) method for quantitative detection of sugarbeet GTSB77 was established.
Erlong LIU   +5 more
doaj   +1 more source

Customer satisfaction, customer delight, customer retention and customer loyalty: Borderlines and insights

open access: yesUncertain Supply Chain Management, 2022
The aim of this study is to investigate the effects of customer satisfaction and customer delight on customer loyalty through customer retention. Data were collected using a questionnaire developed based on the literature and administered to a sample of restaurant customers consisting of 376 customers. Using IBM SPSS and AMOS software for data analyses,
openaire   +1 more source

The Growth and Decay of Custom: The Role of the New Institutional Economics in Economic History [PDF]

open access: yes, 1987
Customs and institutions affect and are affected by economic relations and processes. The two-way interaction is particularly important in studying history where the scale of the temporal canvas ensures that very few variables can be treated as ...
Basu, Kaushik   +2 more
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Fundamentals of protectionism in economic theory

open access: yesУченые записки Российской академии предпринимательства, 2022
The policy of protectionism is aimed at protecting the domestic market, implemented by regulating tax and customs barriers, reducing competition of other countries compared to goods of national producers.
S. S. Repin, L. V. Gogolina
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Customer retaliation at the employee–customer interface

open access: yesJournal of Management & Organization, 2008
AbstractThe service encounter is the point where employees and customers interact both positively and negatively. When things go wrong (service failure), initially it is the employee who is required to remedy the situation (recover the service). While positive service recovery outcomes are well investigated, there is little research that investigates ...
Keeffe, Dominique A.   +2 more
openaire   +3 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Custom, Normative Practice, and the Law [PDF]

open access: yes, 2012
Legally binding custom is conventionally analyzed in terms of two independent elements: regularities of behavior (usus) and convictions of actors engaging in the behavior that it is legally required (opinio juris).
Postema, Gerald J.
core   +3 more sources

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