Results 111 to 120 of about 325,048 (313)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Integrated Border Management at the EU Level. CEPS Working Documents No. 227, 1 August 2005 [PDF]
, 2005 In times marked by trends as diverse as economic globalisation, international migration as well as fear of terrorism and organised crime, the efficient handling of borders has become an issue of political priority, in the EU and across the world. Modern,
Hobbing, Peter.
core
Some legal aspects of the customs services of SGD MF RK in modern conditions
Хабаршы. Заң сериясы, 2017 The article discusses some aspects of the customs services of SRC MF RK in modern conditions. Preliminary findings of the study of the question shows that, in terms of content conceptual changes were measures of fiscal policy and the customs authorities ...
Kurmangali M., Tlepov A.
doaj
Scenario authoring and customization video - HEAT
, 2006 "The Institute of Emergency Services & Homeland Security (IESHS) at Utah Valley State College (UVSC) and the Creative Learning Environment lab (CLE) at Utah State University are engaging in an effort to build an “Emergency Services Training Simulation” for the purposes of helping train emergency services personnel in the communications and procedures ...
Interdisciplinary Media Research Consortium +2 more
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Formation and management of budget flows by custom’s authorities of Russian Federation
RUDN Journal of Economics, 2015 In the article there are described the problems, connected with the budgetary flours’ formation mechanism as the result of the cooperation between the customs organs and the participants VED. The author reveals the special feature of the formation of two
E A Morozova
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source