Results 121 to 130 of about 325,048 (313)
The importance of studying the protection of intellectual property rights in the face of modern challenges and threats, changes in Russia’s economic paradigm, and the search for new competitive advantages in the global economy is undisputed.
Saniyat A. Agamagomedova
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Basing on a wide range of unpublished sources, the paper analyzes the problems of staffing Soviet customs authorities with the examples of Usinskaya and Kosh-Agachskaya customs.
E. A. Vatutin
doaj
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Challenges of Import Customs Clearance in Ethiopian Revenue and Customs Authority
The objective of this study is to identify challenges and prospects of import customs clearance in Ethiopian Revenue & Customs Authority (ERCA). The research method used for this study is qualitative and quantitative (mixed) approach concurrently.
openaire +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A survey of the UK tax system [PDF]
This document provides an overview of the UK tax system, describing how each of the main taxes works and setting their current state into the context of the past 27 ...
Adam, S., Browne, J.
core
In conditions of geopolitical instability, the introduction of a huge number of sanctions against our country, conducting foreign economic activity is becoming more and more difficult and expensive.
A. G. Getman
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

