Results 91 to 100 of about 4,094 (295)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Digitalization in Customs Clearance [PDF]
The introduction of digital customs systems has greatly revolutionized trade facilitation because of reduced clearance times, increased transparency, and minimized trade costs. This study uses a triangulation in methodology where quantitative analysis of
Sarker, Emon
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
CUSTOMS CLEARANCE PROCESS DISCOVERY OF RED LANE IMPORT GOODS
Objective: This research aims to analyze the customs clearance process for the discovery of imported goods in the red lane. Method: This research used a qualitative method with data collection through interviews, observations, and documentation. Results:
Sulistyarini, Galuh Dwi, Luluk Fauziah
core +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Study on Architecture-Oriented Customs Export Clearance Systems Model
Taiwan is an island-based economy with a lack of natural resources. The resources needed by industry almost rely on imports. Many of the products produced need to be exported to foreign markets.
Chen, Shih-Hau
core
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Effects of Procrastination on Customs Clearance Cost: The Case of Kality Customs Branch in Ethiopia
This study has examined factors affecting customs clearance costs in Ethiopian Revenues and Customs Authority, Addis Ababa Kality branch. The main purpose of the study was to investigate the predictors of the customs clearance costs.
Sirika, Debebe Dessalegn
core
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source

