Results 91 to 100 of about 64,241 (304)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An Evaluation of the Need and Cost of Selected Trade Facilitation Measures in Bangladesh: Implications for the WTO Negotiations on Trade Facilitation [PDF]
With the ongoing customs reforms in Bangladesh, the possible future negotiations on trade facilitation in the WTO will have a profound impact on Bangladesh, as well as on other LDC and developing countries.
Debapriya Bhattacharya +1 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
First report on containers [PDF]
Everybody agrees that containers are a "good thing";the actual advantages of transporting cargo, and in particular, dry cargo, in containers over other forms of transport have, to our knowledge, nowhere been stated in quantitative terms.
Kay, E., Pemberton, A. W.
core
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
In recent years Polish customs administration has undergone substantial changes not only in its structure but also in terms of tasks execution. Upon Poland’s accession to the European Union the western border was transformed into the internal border ...
Katarzyna Szmyd
doaj
THE STUDY OF DIFFERENTIATION OF FOREIGN TRADE PRICES BY USING OF DISPERSION ANALYSIS
This article considers the methodological approach for the study of foreign prices of goods by using of dispersion analysis. Currently, one of the problems associated with the avoidance of organizations from the payment of customs duties, is an ...
M B Khudzhatov
doaj +1 more source
ESTIMATION OF THE CUSTOMS CONTROL’S RESULTS UNDER CONDITIONS OF CUSTOM FORMALITIES CLEARANCE
В статье исследованы научные подходы ученых-экономистов к определению сущности таможенного контроля и предложено трактовать данную дефиницию как систему мер, действие которых направлено на предотвращение перемещения товаров через таможенную границу с нарушением требований таможенного законодательства.
openaire +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

