Results 31 to 40 of about 533,716 (307)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Формы правоохранительной деятельности таможенных органов и особенности их реализации [PDF]
, 2017 FORMS OF LAW ENFORCEMENT ACTIVITIES OF CUSTOMS BODIES AND THE FEATURES OF THEIR IMPLEMENTATION J. LUTSEVICHРассматриваются особенности правоохранительной деятельности таможенных органов Республики Беларусь, освещаются особенности правового статуса ...
Луцевич, Ж. А.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Order Without Judges: Customary Adjudication [PDF]
, 2012 Scholarship on custom and law has largely focused on the creation and enforcement of informal rules, demonstrating and in some cases endorsing the existence of order without law.
Blocher, Joseph
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Reflections on Slovak Customs Legislation From the Perspective of the EU Customs Union
Financial Law ReviewThe customs law system within the EU Customs Union is characterized by the coexistence of EU law and national legislation respecting the primacy of EU law.
Adrián Popovič, Soňa Simić
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Customs competencies in ukraine: embracing innovation for enhanced efficiency
Аналітично-порівняльне правознавствоThis article provides a comprehensive analysis of the concept and features of the competencies of Ukrainian customs authorities considering ongoing innovations in the customs sector. As Ukraine follows its Euro-integration path, aimed at modernizing its
A. Nazarko
doaj +1 more source