Results 191 to 200 of about 3,324 (296)

In defence of medical judgement: medicalisation strategies in the daily life of the Lima Asylum in the last third of the 19th century. [PDF]

Med Hist
Amaya Nuñez E.
europepmc   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

Advanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang, Song‐Zuo Xie, Yong‐Zhou Luo, Xin‐Pei Deng, Xi‐Rong Tan, Ze‐Geng Chen, Ling‐Xing Zeng, Gong Chen, Pei‐Rong Ding, Zhi‐Zhong Pan, Rong‐Xin Zhang   +10 more
wiley   +1 more source

Investigating Tourists' Emergency Healthcare Access Barriers: A Systematic Literature Review. [PDF]

Healthcare (Basel)
Peleka P, Aggelopoulou DM, Siskou O.
europepmc   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

Factors Influencing the Willingness to Pay for Wetland Bird Protection: A Value Assessment Based on a Questionnaire Survey of Residents in Gahai Wetland, Gansu, China. [PDF]

Animals (Basel)
Li X, Shi X, Yu T, Du J, Breeze TD.
europepmc   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Evaluating the impact of smart city construction on sewage treatment in China from a synergistic perspective. [PDF]

Sci Rep
Zhang X, Yu X, Hu X.
europepmc   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

Advanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan, Eleonora Vandini, Vedi Kuyil Azhagan Muniraj, Hussien Hammoud, Oussama Jamai, Eve Djenizian, Marc Ramuz, Daniela Giuliani, Manuela Zavatti, Yann Tison, Hervé Martinez, Lucas Teolis, Esma Ismailova, David Moreau, Sébastien Maria, Thierry Djenizian   +15 more
wiley   +1 more source

Impact of China's Accession Protocol on its participation in the WTO dispute settlement mechanism: An analysis of eleven cases involving China's Accession Protocol. [PDF]

Heliyon
Qianyi S.
europepmc   +1 more source

Low‐Power Control Of Resistance Switching Transitions in First‐Order Memristors

Advanced Electronic Materials, EarlyView.
Joule losses are a serious concern in modern integrated circuit design. In this regard, minimizing the energy necessary for programming memristors should be handled with care. This manuscript presents an optimal control framework, allowing to derive energy‐efficient programming voltage protocols for resistance switching devices. Following this approach,
Valeriy A. Slipko, Alon Ascoli, Fernando Corinto, Yuriy V. Pershin   +3 more
wiley   +1 more source