Results 71 to 80 of about 26,876 (298)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 1993 Poster featuring three acrostic poems that read: "Only 'U' can help. Don't do drugs, Report drug use, Understand drugs, Give help to victims, Spread the word. Help Us Reduce Threats. A message from the U.S.
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Інформаційні технології і засоби навчання, 2010 The article deals with the analysis of the problems of open education and distance learning implementation for customs officers according to the international standards developed by the World Customs Organization (WCO).
Olena O. Pavlenko
doaj
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
ІНФОРМАЦІЙНА ТА КОМУНІКАТИВНА КОМПЕТЕНЦІЇ У ПРОФЕСІЙНИХ СТАНДАРТАХ МИТНИКІВ
Інформаційні технології і засоби навчання, 2010 У статті обґрунтовується кореляція комунікативної та інформаційної компетенцій та їх роль як ключових компетенцій у професійній освіті митників. Автор торкається питання визначення сутності понять «інформаційна компетенція», «інформаційна компетентність»,
Olena O. Pavlenko
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Visiting the United States : Customs regulations for nonresidents /
, 1998 Shipping list no.: 98-0332-P.Mode of access ...
U.S. Customs Service.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source