Results 61 to 70 of about 27,278 (294)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Risk Management for Targeting Customs Controls in Developing Countries: A Risky Venture for Revenue Performance? [PDF]

open access: yes
Customs authorities in developing countries are often reluctant to forgo systematic inspections for fear of risking revenue loss. Such physical inspections, however, impede rather than facilitate trade.
Anne-Marie GEOURJON, Bertrand LAPORTE
core  

Increasing the Effectiveness of Preshipment Inspection Services

open access: yes, 2001
Preshipment inspection can help control overinvoicing or underinvoicing of imports, misclassification of imports, and misappropriation of donor funds provided for import support. Of the various objectives
Dutz, Mark
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Tariff evasion and customs corruption : does pre-shipment inspection help? [PDF]

open access: yes
The authors provide a new approach to the evaluation of pre-shipment inspection (PSI) programs as ways of improving tariff-revenue collection and reducing fraud when customs administrations are corrupt. They build a model highlighting the contribution of
Marcelo Olarreaga   +2 more
core  

Implementing the process management mechanism as one of the ways to increase the state customs services quality

open access: yesВестник университета
The existing problematic aspects of the state customs authorities management system in Russia have been studied. The purpose of the study is to analyze the problematic aspects of the current functional (hierarchical) management model, as well as the ...
I. Yu. Sofiyannikova
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Free Zone Incentives in MERCOSUR Countries and WTO Law

open access: yes, 2011
Published source: Gabriel Gari, 'Free Zone Incentives in MERCOSUR Countries and WTO Law' (2011) 6 Global Trade and Customs Journal, Issue 5, pp. 223–244 ID: GTCJ2011031This article examines the consistency of the incentives offered by free zone regimes ...
GARI, G
core  

The Image of the Profession among the Specialists of the Special Working Conditions of Primorsky Region

open access: yesПсихолого-педагогические исследования, 2018
The aim of the research is to describe the image of the profession that the experts of the Border, Police and Customs services have. Today, the future of the Russian Federation mostly depends on these experts’ rate of psychological readiness, level of ...
Lyukshina D.S., Kalita V.V.
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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