Results 131 to 140 of about 1,230 (259)

Family-based community organization in Neolithic Northern China from 8,800 to 7,500 years ago. [PDF]

Innovation (Camb)
Liu T, Zhao Z, Guo M, Cao P, Zhuang L, Zhang W, Liu F, Shi H, Song M, Zhao M, Ju D, Miao B, Fu Q.   +12 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo-Pyridyl Synthetic Cannabinoid Receptor Agonist CH-FUBBMPDORA. [PDF]

Drug Test Anal
Deventer MH, Emanuele MC, Stang BN, Van Uytfanghe K, Masson J, Bouvot X, Lamoureux C, Proposito A, Reniero F, Holland MV, Krotulski AJ, Mannina L, Stove CP, Guillou C.   +13 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Construction of an index system for workplace services by family doctors in China: a two-round Delphi study. [PDF]

BMC Prim Care
Guo J, Yu J, Guo J, Xiao J, Yan X, Liang H, Qian Y, Huang J.   +7 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Finding Home in the Foreign Land: Experience of Indonesian Nurses in Australia. [PDF]

J Multidiscip Healthc
Efendi F, Pradipta RO, Makhfudli M, McKenna L, Houghty GS.   +4 more
europepmc   +1 more source

A Customs Union with a Continuum of Products.

, 1991
This paper analyses the customs union problem in a model containing a continuum of products. The continuum is in three dimensions, so that three countries each have a distinct comparative advantage. Trade patterns are endogenously determined, and changed by policy.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Effectiveness of Ethnic-Cultural Educational Strategies for the Promotion of Breastfeeding. [PDF]

Int J Environ Res Public Health
Hidrobo-Guzmán JF, Morejón-Jácome GE, Cárdenas-Robles ED, Pilco-Vargas LD, Posso López DV, Iguago Angamarca ET.   +5 more
europepmc   +1 more source