Results 151 to 160 of about 12,987,089 (349)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Customs value as a tool for regulating foreign economic activity
У роботі здійснено аналіз сутності, розглянуто еволюцію та правове регулювання митної вартості, її роль у формуванні доходів бюджету та вплив на економіку країни.
Максименко, Т. М.
core
Refugees and “Missing” Arms Trade [PDF]
Millions of people are killed or wounded by small arms each year. The aim of this study is to enhance our understanding of “missing” arms trade across countries. We proceed in two steps.
Gaia Narciso
core
Ethnic-Value Orientations as Social-Psychological Determinants of Ethnophors Socialization
RUDN Journal of Psychology and Pedagogics, 2012 This article analyzes the process of socialization of ethnophors, the determinants of which are ethnic-value orientations. The structural components of the ethnic-value orientations and socialization mechanisms are considered.
R R Nakokhova, I H Ionova
doaj
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Valuation effects of U.S. monetary policy tightening: The roles of foreign exposure. [PDF]
PLoS OneFang X, Peng X.
europepmc +1 more source
Customer value analysis of mass customization
, 2015 Research show that customer patterns in the textile industry are changing and the degree of personalization of products is getting more important to meet personal needs and preferences. Mass customization is a strategy named to create higher customer value by customizing products through a close interaction during the design and production process ...
Martinsson, Kristina, Olsson, Gustav
openaire +1 more source