Results 61 to 70 of about 801,697 (279)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

3D UNDERWATER MINE MODELLING IN THE ¡VAMOS! PROJECT [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
The project Viable Alternative Mine Operating System (¡VAMOS!) develops a novel underwater mining technique for extracting inland mineral deposits in flooded open-cut mines. From a floating launch and recovery vessel a remotely-operated underwater mining
M. Bleier, M. Bleier, C. Almeida, A. Ferreira, R. Pereira, B. Matias, J. Almeida, J. Almeida, J. Pidgeon, J. van der Lucht, K. Schilling, K. Schilling, A. Martins, A. Martins, E. Silva, E. Silva, A. Nüchter, A. Nüchter   +17 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Material management comparison between lot for lot and field actual condition [PDF]

E3S Web of Conferences
Project material management aims to regulate effective and efficient use materials because material is a resource the largest percentage of the total project cost.
Atmaja Jajang, Natalia Monika, Masrilayanti, Ramadhani Siraj, Rahmadini Yessa, Sourkan Sulleyman   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Overview of Intelligent Technology Applications in Open-Cut Tunnel Construction

Buildings
Based on the open-cut tunnel project of Xiong’an New Area in Xiongxin High-speed Railway, this paper studies open-cut tunnel intelligent construction to address low efficiency, difficult quality control and many hidden dangers in traditional construction.
Yifei Ji, Zhongsheng Tan, Li Liao, Dehua Zhang, Zhenliang Zhou   +4 more
doaj   +1 more source

Establishing Control Limits on Time Performance Indicators of Projects through Monte Carlo Simulation and Earned Duration Management [PDF]

فرایند مدیریت و توسعه, 2019
Earned Duration Management (EDM) method has been developed to enhance Earned Value Management and to solve some of its problems, such as separation of measuring time and cost dimensions.
Akbar Alam-Tabriz, Farnoosh Khaledian, Mostafa Mahdipour   +2 more
doaj  

Weighted 1 x 1 Cut-and-Project Sets in Bounded Distance to a Lattice

, 2018
Frettlöh D, Garber A. Weighted 1 x 1 Cut-and-Project Sets in Bounded Distance to a Lattice. DISCRETE & COMPUTATIONAL GEOMETRY. 2019;62(3):649-661.Recent results of Grepstad and Larcher are used to show that weighted cut-and-project sets with one ...
Alexey Garber, Garber, Alexey, Frettlöh, Dirk, Dirk Frettlöh   +3 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cutting Edge Projects in Aurora Participatory Science

Abstract: Participatory science, also called citizen science, connects scientists with the public to enable discovery, engaging broad audiences across the world. In aurora science, direct collaborations, crowdsourced efforts, and community engagement bridge aurora chasers with scientists to do research.
Ledvina, Vincent, MacDonald, Elizabeth, Brandt Edson, Laura, Natsheh, Feras   +3 more
openaire   +3 more sources