Results 91 to 100 of about 752,690 (231)

Equicontinuous factors, proximality and Ellis semigroup for Delone sets [PDF]

open access: yes, 2014
We discuss the application of various concepts from the theory of topological dynamical systems to Delone sets and tilings. We consider in particular, the maximal equicontinuous factor of a Delone dynamical system, the proximality relation and the ...
Aujogue, Jean-baptiste   +3 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Archaeological evaluation : Store Street, Ancoats, Manchester [PDF]

open access: yes, 2017
In March 2017, Salford Archaeology was commissioned by CgMs Consulting to carry out an archaeological evaluation of land between Store Street and Millbank Street in the Ancoats area of Manchester (centred on NGR 385150 398175).
Mottershead, SC
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Multi-Component Model Sets and Invariant Densities

open access: yes, 1998
Model sets (also called cut and project sets) are generalizations of lattices, and multi-component model sets are generalizations of lattices with colourings. In this paper, we study self-similarities of multi-component model sets.
Baake, Michael, Moody, Robert V.
core   +1 more source

On quadrisecant lines of threefolds in P^5 [PDF]

open access: yes, 2000
We study smooth threefolds of the projective space of dimension 5 whose quadrisecant lines don't fill up the space. We give a complete classification of those threefolds X whose only quadrisecant lines are the lines contained in X. Then we prove that, if
Mezzetti, Emilia
core   +4 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Young people not in education, employment or training [PDF]

open access: yes, 2011
"This paper highlights policies and provision that exist for young people not in education, employment or training in Wales. Strategies can cut across many different policy areas and are developed at UK, Welsh and local level. The picture of provision is
O’Toole, Rachel
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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