Results 141 to 150 of about 87,998 (196)

Experimental Investigation of Synergistic Enhanced Oil Recovery by Infill Well Pattern and Chemical Flooding After Polymer Flooding. [PDF]

Gels
Zhang X, Yu J, Liu L, Liu X, Lu X, Feng Q.   +5 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

CONTRAST prioritisation tool: filtering and ranking contaminants of emerging concern in the marine environment using hazard-based approaches. [PDF]

Environ Sci Eur
Yulikayani PY, De Witte B, Ali A, Barber J, Bellas J, Briant N, Brooks S, Bruvold AS, French MA, Hylland K, Kaberi H, León VM, Martins S, Mauffret A, Molinari F, Reid M, Sturve J, Van Poucke C, Valdersnes S, Walgraeve C, Demeestere K, Wennberg AC.   +21 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Mechanistic Characterization and Synergistic Optimization of Residual-Oil Distribution in Low-Permeability Bottom-Water Reservoirs. [PDF]

ACS Omega
Zhang Y, Liu G, Ge S, Wang J, Qu X, Zhen F, Gao Q, Tang X, Cao X, Zhao L.   +9 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Optimization of Chemical Flooding Injection System and Enhanced Oil Recovery after Water Flooding in Block J16, Liaohe Oilfield. [PDF]

ACS Omega
Guo F, Wang J, Zhao S, Xiao C, Li X, Pi Y, Liu L.   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Ultrafast optical gating in a nonlinear lithium niobate microcavity. [PDF]

Sci Adv
Karni O, Vaswani C, Chervy T.
europepmc   +1 more source