Results 41 to 50 of about 746,699 (258)

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Numerical simulation of floating bodies in extreme free surface waves [PDF]

Natural Hazards and Earth System Sciences, 2011
In this paper, we use the in-house Computational Fluid Dynamics (CFD) flow code AMAZON-SC as a numerical wave tank (NWT) to study wave loading on a wave energy converter (WEC) device in heave motion. This is a surface-capturing method for two fluid flows
Z. Z. Hu, D. M. Causon, C. G. Mingham, L. Qian   +3 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Challenges and advantages of cut solar cells for shingling and half-cell modules

EPJ Photovoltaics
Cutting silicon solar cells from their host wafer into smaller cells reduces the output current per cut cell and therefore allows for reduced ohmic losses in series interconnection at module level.
Huyeng Jonas D., Lohmüller Elmar, Shabanzadeh Behnaz, Reichel Christian, Rößler Torsten, Weber Julian, Hofmann Marc, von Kutzleben Daniel, Abdel Latif Najwa, Kraft Achim, Neuhaus Holger, Clement Florian, Preu Ralf   +12 more
doaj   +1 more source

A cut finite element method for spatially resolved energy metabolism models in complex neuro-cell morphologies with minimal remeshing

Advanced Modeling and Simulation in Engineering Sciences, 2021
A thorough understanding of brain metabolism is essential to tackle neurodegenerative diseases. Astrocytes are glial cells which play an important metabolic role by supplying neurons with energy.
Sofia Farina, Susanne Claus, Jack S. Hale, Alexander Skupin, Stéphane P. A. Bordas   +4 more
doaj   +1 more source

Foundations for high-order, conservative cut-cell methods: Stable discretizations on degenerate meshes

Journal of Computational Physics, 2021
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Peter T. Brady, Daniel Livescu
openaire   +3 more sources

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark, Kayla L. Foster, Omar Shakeel, Mary C. Shapiro, Shawki L. Qasim, ZoAnn Dreyer, Eric S. Schafer, Ashley M. Butler, Austin L. Brown, Maria Monica Gramatges   +9 more
wiley   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Training sample selection for space–time adaptive processing based on multi-frames

The Journal of Engineering, 2019
As training samples are not identically distributed with cell under test (CUT) in heterogeneous environments, the performance of space–time adaptive processing (STAP) to suppress clutter degrades. To improve the performance of STAP, this study proposes a
Chenxiao Zhang, Yifeng Wu, Mingming Guo, Xiaobo Deng   +3 more
doaj   +1 more source