Results 91 to 100 of about 206,699 (375)
Skin manifestations associated with checkpoint inhibitors
JEADV Clinical Practice, 2022 Immune checkpoint inhibitors (ICIs) are a relatively novel class of drugs whose administration has been approved for several malignancies. Adverse events are quite common, and the skin is the most frequently involved organ.
Gianluca Nazzaro +4 more
doaj +1 more source
Successful Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Denileukin Diftitox
Case Reports in Oncology, 2022 Primary cutaneous anaplastic large cell lymphoma (PCALCL) is a rare variant of cutaneous T cell lymphoma (CTCL) characterized by CD30-expressing large atypical cells with kidney-shaped nuclei called hallmark cells. Since PCALCL is a rare variant of CTCL,
Mayuko Amagai +7 more
doaj +1 more source
BRAF inhibitor and hairy cell leukemia-related transient acantholytic dermatosis [PDF]
, 2020 Grover disease (GD) is an acquired, nonfamilial, nonimmune mediated, transient or persistent acantholytic dermatosis. Herein, we present a 72-year-old man who had clinical and histopathologic findings of GD following two weeks of treatment with ...
Durkin, John R +3 more
core
Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. [PDF]
, 2013 Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver ...
Blecher-Paz, Karin +10 more
core +1 more source
Advanced Materials Interfaces, EarlyView.CO2 laser ablation, a fast, inexpensive, and reproducible method, is used to create flexible elastomer molds with millimeter‐long cavities for the fabrication of dissolvable polymer needles. Made from PVP, these milli‐needles achieve ≈560 µm penetration into porcine skin, demonstrating their potential for effective transdermal drug delivery.
Matteo Tollemeto +7 more
wiley +1 more source
Journal of Pharmacological Sciences, 2004 Unsei-in inhibits substance P (SP)-induced scratching of mice after repeated administration. The involvement of cutaneous nitric oxide (NO) in the SP-induced scratching led us to investigate the effects of Unsei-in on the cutaneous NO system in mice ...
Tsugunobu Andoh +4 more
doaj
Immunization with antigenic extracts of Leishmania associated with Montanide ISA 763 adjuvant induces partial protection in BALB/c mice against Leishmania (Leishmania) amazonensis infection [PDF]
, 2014 Background/Purpose: A proper adjuvant has a relevant role in vaccine formulations to generate an effective immune response. In this study, total Leishmania antigen (TLA) formulated with Montanide ISA 763 or R848 as adjuvants were evaluated as a first ...
Cargnelutti, Diego Esteban +6 more
core +1 more source
Advanced Science, EarlyView.Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai +12 more
wiley +1 more source
Single Channel Cutaneous Electrogastrography Parameters from Local White Rabbit (Oryctolagus cuniculus) [PDF]
arXiv, 2014 EGG recordings performed on 13 local white rabbits (O. cuniculus) which divided into 3 groups; acetosal 35 mg/kgBM receiver, reserpine 37.5 mg/kgBM receiver, and control group. A total of 72 EGG recordings obtained from them, which divided furthermore into 9 datasets based on prepandrial state, postpandrial state, and post 1 hour drug administration ...
arxiv
Disseminated cutaneous gout: a rare manifestation of a common disease [PDF]
, 2020 Disseminated cutaneous gout is a rare atypical cutaneous manifestation of gout in which widespread dermal and subcutaneous tophi develop at extra-articular body sites.
Adler, Brandon L +4 more
core