Advanced Science, EarlyView.Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu +13 more
wiley +1 more source
Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background About 50 000 new cases of cancer in the United States are attributed to obesity. The adverse effects of obesity on breast cancer may be most profound when affecting the early development; that is, in the womb of a pregnant obese mother.
Fabia de Oliveira Andrade +2 more
wiley +1 more source
A dose-ranging, parallel group, split-face, single-blind phase II study of light emitting diode-red light (LED-RL) for skin scarring prevention: study protocol for a randomized controlled trial. [PDF]
, 2019 BackgroundSkin fibrosis is a significant global health problem that affects over 100 million people annually and has a profoundly negative impact on quality of life.
Heilman, Edward +6 more
core
, 2008 A mosquito larval-pupal survey was conducted in 1,160 households of the Mexican city of Mérida during the rainy season of 2003 to determine their differential productivity for Aedes aegypti.
Che-Medoza, Azael +6 more
core +1 more source
Subacute cutaneous lupus erythematosus as a rare complication of disease-modifying therapy administration in multiple sclerosis: case report [PDF]
, 2023 Ke Xu +6 more
openalex +1 more source
Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles
Advanced Science, EarlyView.Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang +4 more
wiley +1 more source
TREATMENT AND OUTCOME OF HORSES WITH CUTANEOUS PYTHIOSIS, AND META-ANALYSIS OF SIMILAR REPORTS
Slovenian Veterinary Research, 2019 Pythiosis is reported to be one of the most life-threatening infections of people and animals in tropical, subtropical and temperate areas worldwide. Infection can result from ingesting zoospores of Pythium insidiosum organism or from contact with water
Hoda Elkhenany +5 more
doaj +1 more source
Proteomic and phosphoproteomic analysis reveals that neurokinin-1 receptor (NK1R) blockade with aprepitant in human keratinocytes activates a distinct subdomain of EGFR signaling: Implications for the anti-pruritic activity of NK1R antagonists [PDF]
, 2019 Background: Epidermal growth factor receptor (EGFR) inhibitors can cause serious cutaneous toxicities, including pruritus and papulopustular acneiform skin eruptions.
Boozalis, Emily +10 more
core +2 more sources
Cutaneous toxicity with subepidermal blisters and dyskeratosis following administration of pemetrexed in a patient with nivolumab‐induced psoriasis and linear
, 2023 Sayuri Yokomizo +6 more
openalex +1 more source
Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications
Advanced Electronic Materials, EarlyView.This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster +2 more
wiley +1 more source