Results 151 to 160 of about 2,574,537 (354)

CUTANEOUS ADMINISTRATION OF SALICYLATES IN RHEUMATISM, GOUT, ETC. [PDF]

JAMA: The Journal of the American Medical Association, 1898
Dr. Edmund L. Gross of Paris, in a recently published brochure, presents several new ideas. He says that though the various affections classed under gouty or rheumatic often differ widely as to their manifestations, they incontestably possess numerous traits in common.
openaire   +1 more source

Induction of passive cutaneous anaphylaxis by oral administration of antigen.

Journal of Nippon Medical School, 1997
Passive cutaneous anaphylaxis (PCA) reaction was developed by Ovary et al. as an animal model of mainly human type I allergic inflammation reaction. This is the most sensitive reaction for the detection of cutaneously sensitizing antibodies and provides a very effective means by which to investigate immunological reactions concerning the mechanisms of ...
K, Kawasumi, Y, Mizutani, K, Yokomuro, Y, Takeuchi   +3 more
openaire   +3 more sources

Novel locally active estrogens accelerate cutaneous wound healing-part 2 [PDF]

, 2017
Estrogen deprivation is associated with delayed healing, while estrogen replacement therapy (ERT) accelerates acute wound healing and protects against development of chronic wounds.
Bartoli, Gabriele, Bella, Angela La, Brufani, Mario, Ceccacci, Francesca, Ciana, Paolo, D’Aiuto, Virginia, FILOCAMO, Luigi, LEONELLI, Francesca, Maggi, Adriana, MARINI BETTOLO, Rinaldo, Meda, Clara, MIGNECO, Luisa Maria, Rizzi, Nicoletta   +12 more
core   +2 more sources

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Enhanced Engraftment of Mesenchymal Stem Cells in a Cutaneous Wound Model by Culture in Allogenic Species‐Specific Serum and Administration in Fibrin Constructs [PDF]

, 2006
Carl A. Gregory, Emigdio D. Reyes, Mandolin J. Whitney, Jeffrey L. Spees   +3 more
openalex   +1 more source

Lactobacillus Reuteri Vesicles Regulate Mitochondrial Function of Macrophages to Promote Mucosal and Cutaneous Wound Healing

Advancement of science
The interplay between bacteria and their host influences the homeostasis of the human immune microenvironment, and this reciprocal interaction also affects the process of tissue damage repair.
Yuan Chen, Xiaoyao Huang, Anqi Liu, Siyuan Fan, Shiyu Liu, Zihan Li, Xiaoxue Yang, Hao Guo, Meiling Wu, Meng Liu, Peisheng Liu, Fei Fu, Siying Liu, K. Xuan   +13 more
semanticscholar   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Widespread Cutaneous Indeterminate Dendritic Cell Tumor (IDCT) With ETV3::NOAC2 Rearrangement Successfully Treated With PUVA Therapy: A Case Report

Case Reports in Hematology
The unique histiocytic entity of indeterminate dendritic cell tumor (IDCT) is known to cause diagnostic conundrum and treatment dilemmas with no published consensus on either.
Akshay Deshpande, Zbigniew Rudzki, Jaideep Bhat, Matthew Pugh, Susan Rose, Shankara Paneesha   +5 more
doaj   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source