Results 181 to 190 of about 2,501,512 (375)

Hand swelling and other non‐Raynaud's symptoms as the initial presentation of systemic sclerosis: prevalence and clinical associations in two U.S. cohorts

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Raynaud's phenomenon (RP) is often the initial clinical manifestation of systemic sclerosis (SSc), but some patients develop other manifestations first. To help elucidate the diversity of SSc presentation in its early stages, we describe the initial clinical manifestations and antinuclear antibody (ANA) profiles of patients in two early SSc ...
Iqtidar Hanif   +32 more
wiley   +1 more source

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun   +19 more
wiley   +1 more source

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still's Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens   +14 more
wiley   +1 more source

Histological patterns of cutaneous adverse drug reactions

open access: yesHU Revista, 2010
Cutaneous adverse drug reactions (ADR) are skin conditions due to a drug, regardless of the way of administration.  Knowledge about their frequency, clinical manifestations and histopathological patterns is essential for prevention and early diagnosis ...
Sonia Maria Neumann Cupolilo   +5 more
doaj  

A Case Report of Drug‐Induced Hemorrhagic Bullae

open access: yesClinical Case Reports
Hemorrhagic bullae is a rare, non‐immune, cutaneous adverse reaction that happens after the administration of some medicine. This case is a unique report of vancomycin and alteplase‐induced hemorrhagic bullae and warns physicians and healthcare teams to ...
Mehrdad Shavandi   +5 more
doaj   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

open access: yesArthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen   +2 more
wiley   +1 more source

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