Results 191 to 200 of about 206,699 (375)

Engineering antibodies with cancer‐associated binding sites

open access: yesBMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian   +4 more
wiley   +1 more source

Vesicocutaneous fistula due to vesical diverticulitis with stones: A case report and literature review

open access: yesIJU Case Reports, Volume 6, Issue 1, Page 46-50, January 2023., 2023
Introduction We encountered an extremely rare case of a vesicocutaneous fistula due to vesical diverticulitis with stones. Case presentation A 78‐year‐old male patient presented to our department with complaints of suppurative discharge in the suprapubic area. Computed tomography revealed an enlarged prostate, a vesical diverticulum with stones located
Jun Akatsuka   +9 more
wiley   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

open access: yesBMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan   +12 more
wiley   +1 more source

A case of squamous cell carcinoma arising from a suprapubic cystostomy tract in a patient with spinal bifida: Immunohistochemical analysis and literature review

open access: yesIJU Case Reports, Volume 6, Issue 1, Page 60-64, January 2023., 2023
Introduction Squamous cell carcinoma arising from a suprapubic cystostomy tract is a rare complication of an indwelling catheter and is caused by long‐term inflammation and mechanical irritation. Prognosis is relatively poor. Biomarkers in the cancer pathway have not been investigated.
Harutake Sawazaki   +4 more
wiley   +1 more source

Optimizing Peripheral Nerve Block Placement in Hip Surgery: A Cadaveric Study Mapping the Posterior Cutaneous Innervation

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Optimizing analgesia after hip surgery enables more rapid recovery. However, peripheral nerve blocks (PNBs) often fail to provide adequate pain relief in the posterolateral hip as they typically target the lateral cutaneous nerve of the thigh (LCNT).
Ziki Gurney   +5 more
wiley   +1 more source

Rational corticosteroids administration and antibiotic treatment is key to managing cutaneous anthrax

open access: yesBMC Infectious Diseases
Anthrax is a global health concern, with cutaneous anthrax accounting for over 95% of cases and generally promising outcomes. Nonetheless, the absence of timely intervention can result in mortality rates of 10-40%. This research aims to explore the clinical presentations and phenotypic characteristics of cutaneous anthrax patients and evaluate the ...
Luo Xia   +6 more
openaire   +3 more sources

Subcutaneous Panniculitis‐like T‐cell Lymphoma

open access: yes
Arthritis &Rheumatology, Accepted Article.
Shae Chambers   +2 more
wiley   +1 more source

Breaking barriers: Smart vaccine platforms for cancer immunomodulation

open access: yesCancer Communications, EarlyView.
Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari   +11 more
wiley   +1 more source

Comparing VIP and PD‐L1 expression as cancer biomarkers

open access: yesImmunoMedicine, Volume 2, Issue 2, December 2022., 2022
Abstract Immune checkpoint molecules are critical targets of cancer therapies due to their ability to modulate immune responses to cancer. Vasoactive intestinal peptide (VIP) has been proposed as an immune checkpoint molecule, but its predictive and prognostic values have not been established.
Jojo Y. Liu   +6 more
wiley   +1 more source

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