ABSTRACT Background In recent years, smaller‐volume radiotherapy has attracted attention. It appears to be a safe and effective treatment for glottic laryngeal cancer. This study evaluated the results of ultra‐hypofractionated radiotherapy for early glottic laryngeal cancer in unfit patients.
Mete Gundog, Esin Kiraz
wiley +1 more source
Pharmacovigilance study for the identification of mogamulizumab-induced immune-related adverse events using a real-world database. [PDF]
Miyata K+13 more
europepmc +1 more source
Olive Oil Administration Improves Cutaneous Wound Healing of Pressure Ulcers in Mice
Andréa Monte‐Alto‐Costa+2 more
openalex +1 more source
SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai+6 more
wiley +1 more source
What's New? While melanoma vaccines have shown therapeutic promise, predicting their clinical benefits is challenged by factors such as delayed response to immunotherapy and scarcity of biomarkers. Here, the authors examined the long‐term efficacy of vaccination with either 4 or 12 class I MHC‐restricted peptides in high‐risk melanoma.
Emily K. Ninmer+3 more
wiley +1 more source
Multi-Organ Adverse Reaction to Two Hypomethylating Agents: A Challenge in High-Risk Myelodysplastic Syndrome Treatment. [PDF]
Alves SB, Pierdomenico F.
europepmc +1 more source
Surgical site infections and sepsis in gynecological surgery
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento+13 more
wiley +1 more source
Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PAR2, in preclinical models of migraine. [PDF]
Kopruszinski CM+15 more
europepmc +1 more source
TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer
This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin+7 more
wiley +1 more source
Exposed Necrotic Bone in a Head and Neck Cancer Patient: Report of a Diagnostic Challenge. [PDF]
Dell'Olio F+5 more
europepmc +1 more source