Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang+12 more
wiley +1 more source
Diagnosis and management of reactive infectious mucocutaneous eruption
Abstract Medicine's clinical understanding of reactive infectious mucocutaneous eruption (RIME) has evolved over time. It was previously described as Mycoplasma pneumoniae‐induced rash and mucositis (MIRM), and before that as a variant of Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis. Here, we summarize the current understanding of best practices
Nicole Damari+2 more
wiley +1 more source
New-onset dermatomyositis in a patient on nivolumab for metastatic melanoma. [PDF]
Curkovic NB, Johnson DB, Parker ER.
europepmc +1 more source
A Novel In Vitro Host−Pathogen Model for Felis catus and Sporothrix Zoonotic Species Investigation
ABSTRACT Hyperendemic zoonotic sporotrichosis, attributed to Sporothrix brasiliensis, presents a significant public health challenge in Brazil. Cats exhibit severe symptoms and high fungal loads, though their susceptibility is unclear. Sporothrix schenckii can also cause feline disease, primarily seen in Asia.
Gabriele Barros Mothé+10 more
wiley +1 more source
Integrated diagnosis and successful treatment of imported old world cutaneous leishmaniasis with intralesional sodium stibogluconate in china: a case report. [PDF]
Xu J, Xia X, Liu Z.
europepmc +1 more source
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine+24 more
wiley +1 more source
Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Afimetoran, a Toll-Like Receptor 7 and 8 Inhibitor, in Patients With Cutaneous Lupus Erythematosus: A Phase 1b Randomized, Double-Blind, Placebo-Controlled Study. [PDF]
Hosein F+13 more
europepmc +1 more source
Abstract Gastrointestinal (GI) bleeding can be a common symptom in the pediatric population. Vascular malformations, which cause symptoms based on their location and effect on surrounding structures, are an uncommon cause of GI bleeding. We present the case of a 6‐year‐old male with a 1‐year history of hematochezia, constipation, and microcytic anemia.
Kathleen Ordas+5 more
wiley +1 more source
The First Dorsal Metatarsal Artery Perforator Flap: A Description and Anatomical Study. [PDF]
Saboye M+5 more
europepmc +1 more source