Pemphigus is an autoimmune mucocutaneous blistering disease caused by autoantibodies against desmogleins. Rituximab effectively treats pemphigus by inducing remission and rapidly reducing corticosteroid dosage.
Ahreum Song+8 more
doaj +1 more source
Efficacy of Thermotherapy to Treat Cutaneous Leishmaniasis Caused by Leishmania tropica in Kabul, Afghanistan: A Randomized, Controlled Trial [PDF]
BACKGROUND: Pentavalent antimony is the agent recommended for treatment of cutaneous leishmaniasis (CL). Its use is problematic, because it is expensive and because of the potential for drug-associated adverse effects during a lengthy and painful ...
Aram H+23 more
core +1 more source
Ethosomes and organogels for cutaneous administration of crocin
The present study describes the production and characterization of phosphatidylcholine based ethosomes and organogels, as percutaneous delivery systems for crocin. Crocin presence did not influence ethosome morphology, while the drug slightly increased ethosome mean diameter.
Esposito E+6 more
openaire +5 more sources
The standard of care for cutaneous leishmaniasis includes the intramuscular/intravenous administration of pentavalent antimonials that are toxic and poorly tolerated.
Ernesto Rojas Cabrera+9 more
doaj +1 more source
Heat emitting damage in skin: a thermal pathway for mechanical algesia [PDF]
Mechanical pain (or mechanical algesia) can both be a vital mechanism warning us for dangers or an undesired medical symptom important to mitigate. Thus, a comprehensive understanding of the different mechanisms of this type of pain is paramount. In this work, we study the tearing of porcine skin in front of an infrared camera, and show that mechanical
arxiv +1 more source
Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure [PDF]
Air pollution is linked to increased emergency department visits for headache and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood.
Hurley, Joyce Harts+4 more
core +1 more source
Anaphylaxis following administration of extracorporeal photopheresis for cutaneous T cell lymphoma [PDF]
Extracorporeal photopheresis is a non-invasive therapy used for the treatment of a range of T cell disorders, including cutaneous T cell lymphoma. During extracorporeal photopheresis, peripheral blood is removed from the patient and the white blood cells are separated from whole blood via centrifugation. The white blood cells are exposed to psoralen (a
Lisa M. Morris+5 more
openaire +3 more sources
Cutaneous Adverse Events in Newly Approved FDA Non-cancer Drugs: A Systematic Review
The prevalence of cutaneous adverse events attributable to newly approved anti-cancer drugs has been well reviewed in the dermatologic literature. In contrast, over 75% of US Food and Drug Administration approvals in the past 5 years have been for non ...
Paul C. Macklis+5 more
doaj +1 more source
HaptiX: Vibrotactile Haptic Feedback for Communication of 3D Directional Cues [PDF]
In Human-Computer-Interaction, vibrotactile haptic feedback offers the advantage of being independent of any visual perception of the environment. Most importantly, the user's field of view is not obscured by user interface elements, and the visual sense is not unnecessarily strained.
arxiv +1 more source
The relationship between local scalp skin temperature and cutaneous perfusion during scalp cooling [PDF]
Cooling the scalp during administration of chemotherapy can prevent hair loss. It reduces both skin blood flow and hair follicle temperature, thus affecting drug supply and drug effect in the hair follicle. The extent to which these mechanisms contribute
Janssen, Francis-Paul E.M.+4 more
core +4 more sources