Results 21 to 30 of about 136,464 (163)

Evaluation of Hydrogel Suppositories for Delivery of 5-Aminolevulinic Acid and Hematoporphyrin Monomethyl Ether to Rectal Tumors

Molecules, 2016
We evaluated the potential utility of hydrogels for delivery of the photosensitizing agents 5-aminolevulinic acid (ALA) and hematoporphyrin monomethyl ether (HMME) to rectal tumors.
Xuying Ye, Huijuan Yin, Yu Lu, Haixia Zhang, Han Wang   +4 more
doaj   +1 more source

Successful outcome of mucormycosis in two children on induction therapy for acute lymphoblastic leukemia

Indian Journal of Medical and Paediatric Oncology, 2013
Zygomycetes are one of the less common causes of invasive fungal infections in patients with the hematological malignancies. We report two cases of acute lymphoblastic leukemia in the pediatric age group, complicated by disseminated cutaneous ...
Anshul Gupta, Sandeep Jain, Charu Agrawal, Gauri Kapoor   +3 more
doaj   +1 more source

Therapeutic advances in the topical treatment of cutaneous leishmaniasis: A review.

PLoS Neglected Tropical Diseases, 2021
Cutaneous leishmaniasis has been endemic since decades. Millions of cases are reported worldwide specially in developing and underdeveloped countries. There are 2 major types of cutaneous leishmaniasis based on the causating species found in different ...
Marium Azim, Saeed Ahmad Khan, Saleem Ullah, Shafiq Ullah, Syed Ishtiaq Anjum   +4 more
doaj   +1 more source

Ethosomes and organogels for cutaneous administration of crocin

Biomedical Microdevices, 2016
The present study describes the production and characterization of phosphatidylcholine based ethosomes and organogels, as percutaneous delivery systems for crocin. Crocin presence did not influence ethosome morphology, while the drug slightly increased ethosome mean diameter.
Esposito E, Drechsler M, Huang N, Pavoni G, Cortesi R, Santonocito D, PUGLIA, CARMELO   +6 more
openaire   +4 more sources

Gellan Nanohydrogels: Novel Nanodelivery Systems for Cutaneous Administration of Piroxicam [PDF]

Molecular Pharmaceutics, 2018
The feasibility to use gellan nanohydrogels (Ge-NHs) as delivery system for the cutaneous administration of piroxicam (PRX) was investigated using gellan conjugated with cholesterol or riboflavin. The in vitro skin penetration studies through human epidermis were performed using a saturated aqueous drug solution, a 50% w/v Transcutol aqueous solution ...
Musazzi, Umberto M, Cencetti, Claudia, Franzé, Silvia, Zoratto, Nicole, Di Meo, Chiara, Procacci, Patrizia, Matricardi, Pietro, Cilurzo, Francesco   +7 more
openaire   +4 more sources

Topical Percutaneous Drug Delivery for Allergic Diseases: A Novel Strategy for Site-Directed Pharmacologic Modulation

Pharmaceutics
Topical percutaneous drug delivery has recently emerged as a novel strategy for the treatment of allergic diseases, offering targeted drug delivery to mucosal tissues adjacent to the skin.
Mitsuhiro Kamimura, Hiroaki Todo, Kenji Sugibayashi, Koichiro Asano   +3 more
doaj   +1 more source

Clonazepam-induced lichenoid drug eruption: a case report

BMC Psychiatry, 2021
Background Lichenoid drug eruption is rare and can mimic idiopathic lichen planus and other dermatoses. Clonazepam, a commonly used drug for the treatment of anxiety-related disorders and seizures, is known to be an unlikely cause of cutaneous adverse ...
Hee Won Yang, Jong Bin Bae, Jung-Im Na, Ki Woong Kim   +3 more
doaj   +1 more source

The effect of 17β-estradiol on cutaneous wound healing in protein-malnourished ovariectomized female mouse model.

PLoS ONE, 2014
Cutaneous wound healing is delayed by protein malnutrition (PM). On the other hand, estrogen promotes cutaneous wound healing by its anti-inflammatory and cell proliferation effects.
Kanae Mukai, Emi Komatsu, Yukari Nakajima, Tamae Urai, Nasruddin, Junko Sugama, Toshio Nakatani   +6 more
doaj   +1 more source

Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males

Journal of Translational Medicine, 2022
Background We hypothesized that a gender difference in clinical response may exist to adjuvant CTLA4 blockade with ipilimumab versus high-dose IFNα (HDI).
Mariam Saad, Sandra J. Lee, Aik Choon Tan, Issam M. El Naqa, F. Stephen Hodi, Lisa H. Butterfield, William A. LaFramboise, Walter Storkus, Arivarasan D. Karunamurthy, Jose Conejo-Garcia, Patrick Hwu, Howard Streicher, Vernon K. Sondak, John M. Kirkwood, Ahmad A. Tarhini   +14 more
doaj   +1 more source

Life-threatening rocuronium-induced anaphylactic shock without cutaneous manifestations successfully reversed with sugammadex: a case report

JA Clinical Reports, 2020
Background Recognition of rocuronium-induced anaphylaxis is often challenging, owing to its diverse clinical manifestations. Regarding treatment, several reports have described the efficacy of sugammadex, while conflicting reports have also been ...
Yoshiaki Takise, Jungo Kato, Tomohiro Suhara, Takashige Yamada, Takeru Funakoshi, Hayato Takahashi, Masayuki Amagai, Hiroshi Morisaki   +7 more
doaj   +1 more source