Results 131 to 140 of about 23,535 (265)

From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management

JCC Plus, Volume 1, Issue 2, March 2026.
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi, Alejandra A. Carriles, Samuel Elias Pineda Chavez, Stefanos Bonovas, Arianna Dal Buono, Cristina Bezzio, Alessandro Armuzzi, Stefania Vetrano   +7 more
wiley   +1 more source

Fluorapatite‐Coated Percutaneous Osseointegrated Prostheses Limit Epidermal Downgrowth and Promote Periprosthetic Healing in a Weight‐Bearing Sheep Model—A Preliminary Study

Journal of Orthopaedic Research, Volume 44, Issue 3, March 2026.
ABSTRACT Percutaneous osseointegrated (OI) devices offer an advanced alternative to socket prosthetic suspension systems for amputees but can face clinical limitations due to complications at the skin‐implant interface. Titanium (Ti) and its alloys, though mechanically suitable and promoting osseointegration, are unable to support epidermal cell ...
Samantha K. Steyl, James P. Beck, Jill Shea, Ruben Sundramurti, David Rou, Kent N. Bachus, Jay Agarwal, Sujee Jeyapalina   +7 more
wiley   +1 more source

Late Development of a Bronchocutaneous Fistula due to an Epicardial Cardioverter-Defibrillator Lead

Journal of Tehran University Heart Center, 2015
Cutaneous complications caused by a pacemaker or defibrillator are widely documented, but the development of a bronchocutaneous fistula has never been described before. We report the case of a 79-year-old man who was admitted to our hospital because of a
Vasileios Patris, Orestis Argiriou, Niki Lama, Haris Georgiou, Constantine Halkias, Christos Charitos   +5 more
doaj  

Cutaneous Fistula [PDF]

, 2020
openaire   +1 more source

Efficacy and Safety of DNV3 (a Lymphocyte‐activation Gene 3–blocking Antibody) Combined With Toripalimab and Chemotherapy in Advanced Melanoma: An Open‐label, Single‐arm Clinical Trial

MedComm, Volume 7, Issue 3, March 2026.
This investigator‐initiated trial demonstrates that LAG‐3/PD‐1 dual blockade (DNV3 + toripalimab) combined with chemotherapy achieves a 44.4% overall response rate (ORR) in advanced melanoma, showing particular efficacy in anti‐PD‐(L)1‐resistant patients (42.9% ORR, 7.36‐month median PFS), treatment‐naïve mucosal melanoma (50.0% ORR), and those with ...
Jing Lin, Lizhu Chen, Ling Chen, Dingyi Wang, Yuping Lu, Huishan Zhang, Ping Chen, Wei Yan, Zuoxiang Xiao, Yu Chen   +9 more
wiley   +1 more source

Ruptured pseudo-aneurysm of a femoral artery in a drug abuser revealed by post-mortem CT angiography [PDF]

, 2018
A 35-year-old drug addict was found dead in a public toilet with a ruptured groin, which was later diagnosed to be a leaking pseudo-aneurysm. Investigation at the scene revealed impressive external hemorrhage related to a groin wound.
Augsburger, Marc, Doenz, Franceso, Grabherr, Silke, Lesta, Maria, Mangin, Patrice, Michaud, Katarzyna   +5 more
core  

Exploration of Therapeutic Targets Using CDK4 Inhibitors for Head and Neck Mucosal Melanoma

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 3, Page 784-791, March 2026.
Abstract Objective Mucosal melanoma (MM) is an extremely aggressive malignant tumor in the head and neck region associated with a poor prognosis. In the present study, we conducted cell proliferation assay and western blotting using cell lines derived from MM and the immunohistochemical analysis of pathological MM tissues to identify novel therapeutic ...
Takayoshi Hattori, Makiko Fujii, Tsutomu Ueda, Akira Ishikawa, Yuichi Mine, Bingwen Xu, Tomoya Suehiro, Minoru Hattori, Hiroaki Tahara, Yuki Sato, Nobuyuki Chikuie, Takayuki Taruya, Takao Hamamoto, Takashi Ishino, Sachio Takeno   +14 more
wiley   +1 more source

Impact of prenatal sirolimus on cardiac rhabdomyomas and brain tubers

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 350-359, March 2026.
ABSTRACT Objective To document the natural progression of fetal cardiac rhabdomyomas and evaluate the impact of prenatal sirolimus (PNS) on tumor size, cardiac complications and brain‐tuber size. Methods This was a single‐center retrospective cohort study of pregnancies with suspected fetal cardiac rhabdomyoma referred to our center from April 2013 to ...
S. Vergote, L. Van der Veeken, D. Chitayat, E. Jaeggi, G. Ryan, E. Miller, S. Shinar   +6 more
wiley   +1 more source

Gastropleurocutaneous fistula secondary to cement prosthesis migration: A rare late complication of chest wall sarcoma reconstruction

BMC Surgery
Background Gastropleurocutaneous fistula (GPCF) is a rare, potentially life-threatening condition defined by an abnormal connection between the stomach and the pleural cavity with an accompanying cutaneous tract.
Mohammad Alaa Aldakak, Nawwar Fallouh, Bassel Ibrahim, Ahmad Al Dalati, Yousef Al Jabban, Bassam Darwish, Yehia Taifour   +6 more
doaj   +1 more source

New concepts of reconstructive techniques with human amniotic membrane in pelvic floor surgery [PDF]

, 2018
1. SUMMARY Due to the aging of society and the growing number of oncology cases, there is a need for new and efficient reconstruction techniques in urology.
Barski Dimitri
core