Results 141 to 150 of about 27,354 (241)

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

Association Between Cutaneous Lupus Erythematosus and Atherosclerotic Cardiovascular Disease: A Systematic Review. [PDF]

Clin Cosmet Investig Dermatol
Althobaiti RF, Almansour TA, Altowairqi RK, Alzahrani NM, Samman LA, Almutairi NA, Aljoudi SB, Alharbi RH.   +7 more
europepmc   +1 more source

Nucleotide Metabolism in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao, Yiyu Zeng, Yike Xu, Shu Rao, Mouna Khouchani, Hassna Soummane, Jingyi Li, Rui Liu   +7 more
wiley   +1 more source

Proinflammatory keratinocytes drive a novel mouse model of autoimmunity with systemic and cutaneous lupus erythematosus. [PDF]

Immun Inflamm
Tian J, Shi L, Zhang D, Yao X, Lu J, Zhao M, Lu Q.   +6 more
europepmc   +1 more source

Clinical Images: Subcutaneous panniculitis‐like T cell lymphoma

Arthritis &Rheumatology, Volume 78, Issue 8, Page 1799-1800, August 2026.
S Chambers, CN Myrdal, VP Werth
wiley   +1 more source

A Serum N‐Glycan Ratio Associated With Disease Severity and Treatment Response in Psoriasis

The Journal of Dermatology, Volume 53, Issue 8, Page 1090-1098, August 2026.
ABSTRACT Psoriasis is a chronic, immune‐mediated inflammatory disease with heterogeneous manifestations. Reliable biomarkers reflecting disease severity and treatment response remain limited. Glycans—carbohydrate structures attached to proteins and lipids—play key roles in biological processes, contributing to functional specificity.
Kentarou Nishimura, Noritaka Oyama, Takumi Hasegawa, Hiroshi Kasamatsu, Takenao Chino, Takahiro Tokunaga, Kiyoshi Higashi, Koichi Saito, Keita Yamada, Minoru Hasegawa   +9 more
wiley   +1 more source

Case Report: Extracorporeal photopheresis for cutaneous lupus erythematosus induces putatively atheroprotective B and T cell responses. [PDF]

Front Immunol
Visentini M, Ozsvar-Kozma M, Pacella I, Pinzon Grimaldos A, Falco F, Shafii-Bafti M, Minicocci I, La Gualana F, Carlesimo M, Casato M, Basili S, Arca M, Piconese S, Fiorilli M, Binder CJ.   +14 more
europepmc   +1 more source

Cross-tissue integrative transcriptomic and multimodal analyses suggest shared immune signatures linking lupus nephritis and cutaneous lupus erythematosus. [PDF]

Front Immunol
Li M, Song C, Wang Z, Yuan H, Zhang Z, Sun Y, Zhang F, Wang S, Sun H, Zhao H, Zhu L, Wang D, Li Y.   +12 more
europepmc   +1 more source

Interleukin‐40 in Systemic Sclerosis: A Treatment‐Sensitive Marker of Immune Modulation Rather Than Disease Activity

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Interleukin‐40 (IL‐40) is a recently identified cytokine primarily produced by activated B cells and implicated in immune regulation across several autoimmune diseases. Although B cell–driven immune dysregulation plays a central role in systemic sclerosis (SSc), the circulating behavior and clinical relevance of IL‐40 in this disease remain ...
İbrahim Vasi, Emin Ümit Bağrıaçık, Rıza Can Kardaş, Nihan Örüklü, Melek Yaman, Derya Yıldırım, Burcugül Kaya, Rahime Duran, İbrahim Karaduman, İbrahim Yahya Çakır, Hamit Küçük, Berna Göker, Abdulsamet Erden, Mehmet Akif Öztürk   +13 more
wiley   +1 more source

Ashes to Rashes: An Exploration of the Intersection Between Smoking and Cutaneous Lupus Erythematosus. [PDF]

Biomolecules
Homer RO, Eldaboush A, Kang D, Ahmed NS, Khosravi-Hafshejani T, Liu ML, Werth VP.   +6 more
europepmc   +1 more source