Results 41 to 50 of about 28,938 (229)

Recalcitrant Eyelid Lupus Treated With Topical Ruxolitinib

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Lupus of the eyelids, or lupus blepharitis, is a rare and localized form of chronic cutaneous lupus. The use of topical corticosteroids is limited in this sensitive area due to the risk of adverse events. We present a case of eyelid lupus, with histological confirmation, resistant to multiple lines of treatment, successfully treated with ...
Clémence Bertold   +6 more
wiley   +1 more source

Effects of rituximab-based B-cell depletion therapy on skin manifestations of lupus erythematosus--report of 17 cases and review of the literature

open access: yes, 2013
Cutaneous manifestations occur frequently in systemic lupus erythematosus (SLE) and are pathognomonic in subacute-cutaneous lupus erythematosus (SCLE) and chronic cutaneous lupus erythematosus (CCLE).
Morris, SD   +3 more
core  

Cutaneous Manifestations of Lupus Erythematosus in Antananarivo (Madagascar)

open access: yes, 2019
Introduction: Lupus erythematosus is a serious autoimmune inflammatory disease. Mucocutaneous manifestations are themain clinical manifestations, so our aim is to determine the different cutaneous manifestations of lupus erythematosus in Antananarivo ...
RAPELANORO RABENJA, Fahafahantsoa   +5 more
core   +1 more source

Nail Disorders in Systemic Conditions

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

A review of the evidence and cost of therapies for cutaneous lupus erythematosus

open access: yes, 2019
Cutaneous lupus erythematosus (CLE)—a common presentation of lupus erythematosus—may exist independently or as a part of the systemic manifestations of systemic lupus erythematosus.
Rosen, J D, Maderal, A, Paul, S
core   +1 more source

Impact of Co‐Morbid Immunocompromise in HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

open access: yesThe Laryngoscope, EarlyView.
Among patients with surgically resected Human Papillomavirus positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC), immunocompromised patients had significantly worse overall survival compared to the non‐compromised group; however, these exploratory findings should be interpreted cautiously.
Maxwell L. Weng   +7 more
wiley   +1 more source

Methotrexate therapy in systemic lupus erythematosus

open access: yes, 2001
There are 12 non-controlled and only two controlled studies using methotrexate (MTX) in a total of 207 SLE patients in the literature. the majority of these studies evaluated mainly cutaneous and/or articular involvement and attained good results.
Sato, E. I.
core   +1 more source

Apoptosis in chronic cutaneous lupus erythematosus, discoid lupus, and lupus profundus [PDF]

open access: yes, 2015
: Introduction: Lupus erythematosus is a multisystemic disease that is characterized by autoantibody production and immune complex deposition in such tissues as the mucosa, joints, the central nervous system, and skin.
Felipe de Jesús, Torres del Muro   +7 more
core   +1 more source

An Open‐Label Phase 1b Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of ANX005 in Patients with Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Complement activation is implicated in Huntington's disease; ANX005 is a potent inhibitor of component C1q. ANX005 exhibited a generally manageable safety profile with rapid reduction in C1q in the cerebrospinal fluid. Functional ability on composite Unified Huntington's Disease Rating Scale and total functional capacity was maintained, with potential ...
Rajeev Kumar   +15 more
wiley   +1 more source

Lupus erythematosus [PDF]

open access: yes, 2015
Eritemski lupus (LE; engl. lupus erythematosus) je upalna multisistemska autoimuna bolest vezivnog tkiva koja u značajnoj mjeri zahvaća kožu. Zasada je nepoznate etiologije i vrlo je varijabilne kliničke slike.
Diminić, Ivana
core  

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