Results 281 to 290 of about 101,476 (335)

Rituximab in cutaneous B-cell lymphoma: a report of two cases

, 2000
R.A. Sabroe, Fiona Child, Alison J.‐A. Woolford, M.F. Spittle, R. Russell‐Jones   +4 more
openalex   +1 more source

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

CA: A Cancer Journal for Clinicians, Volume 75, Issue 4, Page 282-307, July/August 2025.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari, Johnson Ung, Jeffrey W. Craig, Kallesh D. Jayappa, Ipsita Pal, David J. Feith, Thomas P. Loughran Jr, Owen A. O’Connor   +7 more
wiley   +1 more source

Cutaneous T Cell Lymphoma Reactive CD4+ Cytotoxic T Lymphocyte Clones Display a Th1 Cytokine Profile and Use a Fas-Independent Pathway for Specific Tumor Cell Lysis

, 2000
Hamid Echchakir, Martine Bagot, Guillaume Dorothée, Denis Martinvalet, Sabine Le Gouvello, Laurence Boumsell, Salem Chouaı̈b, Armand Bensussan, Fathia Mami‐Chouaib   +8 more
openalex   +1 more source

Cancer treatment and survivorship statistics, 2025

CA: A Cancer Journal for Clinicians, Volume 75, Issue 4, Page 308-340, July/August 2025.
Abstract The number of people living with a history of cancer in the United States continues to rise because of the growth and aging of the population as well as improved survival through advances in early detection and treatment. To assist the public health community serve the needs of these survivors, the American Cancer Society and the National ...
Nikita Sandeep Wagle, Leticia Nogueira, Theresa P. Devasia, Angela B. Mariotto, K. Robin Yabroff, Farhad Islami, Ahmedin Jemal, Rick Alteri, Patricia A. Ganz, Rebecca L. Siegel   +9 more
wiley   +1 more source

Administration of nivolumab plus ipilimumab: Infusion of the fixed‐ratio combination versus sequential infusions in two randomized controlled trials of metastatic melanoma (CheckMate 742) and renal cell carcinoma (CheckMate 800)

Cancer, Volume 131, Issue 14, 15 July 2025.
Abstract Background Immune checkpoint inhibitors can be coadministered as a fixed‐ratio combination (FRC) or administered as sequential infusions (ASI). Two randomized, open‐label trials compared nivolumab + ipilimumab as a FRC versus ASI in patients with melanoma or renal cell carcinoma.
Alexander M. Menzies, Pamela Salman, Osvaldo Arén Frontera, David Pook, Christopher M. Hocking, Yousef Zakharia, Howard Gurney, Craig Gedye, Jeffrey C. Goh, Bijoy Telivala, Jean‐Jacques Grob, Céleste Lebbé, Luis de la Cruz Merino, Laurent Machet, Eve‐Marie Neidhardt, Anila Qureshi, Fareeda Hosein, Lora Hamuro, Burcin Simsek, Asim Amin   +19 more
wiley   +1 more source

MS275 Inhibits Neuroblastoma Cell Growth by Mediating H3K27ac/PROX1 Axis In Silico and In Vitro

The FASEB Journal, Volume 39, Issue 13, 15 July 2025.
Our study demonstrates that MS275, a selective HDAC inhibitor, suppresses HDAC1/3 protein expression, leading to hyperacetylation of histone H3 at lysine 27 (H3K27ac) within the PROX1 promoter region (−608 to −508). This epigenetic modification upregulates PROX1 transcription, which subsequently modulates key cellular processes, including cell cycle ...
Chao Yuan, Chaoqun Li, Junwei Lu, Shengjie Liao, Runkun Wu, Duanzhuo Li, Mi Huang, Dacong Gong, Weibin Wu, Xin Yu, Shinuan Fei, Wenxia Si   +11 more
wiley   +1 more source

Detection of residual host cells after bone marrow transplantation using non-isotopic in situ hybridization [PDF]

, 1993
Cremer, Thomas, Knuutila, Sakari, Popp, Susanne, Ruutu, Tapani, Volin, L., Wessman, M.   +5 more
core  

Modified total skin electron treatment for a paraplegic patient

Journal of Applied Clinical Medical Physics, Volume 26, Issue 7, July 2025.
Abstract Total Skin Electron Therapy (TSET) has been a highly effective treatment for mycosis fungoides (MF). However, the standard TSET treatment requires the patient to stand upright in six different positions for an extended time period, which may not be possible for some patients.
Thomas Martin, Geoff Nelson, David Gaffney, Christian Dial, Martin Szegedi, Prema Rassiah   +5 more
wiley   +1 more source

Sézary Syndrome—Eosinophilia Explained by a Blood Film

American Journal of Hematology, Volume 100, Issue 8, Page 1423-1424, August 2025.
Merel T. A. Soeterik, Joris Janssen, Leo M. Budel, Anton W. Langerak, Yorick Sandberg, Barbara J. Bain   +5 more
wiley   +1 more source

Commissioning and clinical implementation of low dose dual‐field rotational TSET

Journal of Applied Clinical Medical Physics, Volume 26, Issue 7, July 2025.
Abstract Background Total skin electron therapy (TSET) is a specialized technique for treating cutaneous T‐cell lymphomas, such as mycosis fungoides. While traditional TSET regimens prescribe 30–36 Gy, low dose TSET at 12 Gy has gained attention due to its reduced toxicity.
Broderick Ivan McCallum‐Hee, Mounir Ibrahim, Godfrey Mukwada, Pejman Rowshanfarzad, Joshua Dass, Jude Dewitt, Robert Parin, Gregory Withey, Zaid Alkhatib   +8 more
wiley   +1 more source