CD30-positive cutaneous lymphoma: report of four cases with an emphasis on clinicopathological correlations [PDF]
: The classification of cutaneous lymphomas is multidisciplinary and requires the correlation between clinical, histopathological, immunohistochemical, and molecular diagnostic elements. In this article, we present four different cases of CD30-positive T-
Thiago Jeunon de Sousa Vargas +2 more
doaj +2 more sources
Primary cutaneous anaplastic large-cell lymphoma in a patient with Hodgkin’s disease – case report
Introduction. Cutaneous anaplastic large cell lymphoma (C-ALCL) is one of the CD30+ lymphoproliferative disorders. Usually it has a mild course and does not require aggressive treatment. The prognosis in C-ALCL is good, with the 10-year survival rate
Dorota Kozłowska +2 more
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Primary cutaneous follicle center lymphoma [PDF]
Cutaneous lymphomas are classified according to their cellular origin into T-cell lymphoma and B-cell lymphoma. The annual incidence rate is 0.3 per 100,000 population. We report a case of a 56-year-old male patient who presented with a two-month history
Eline Pinheiro Weba Costa +17 more
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Molecular Pathogenesis of MALT lymphoma
Mucosa associated lymphoid tissue (MALT) lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway.
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Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Cutaneous Lymphoma in a Tertiary Skin Hospital and Referral Centre in Nepal
Background: Primary cutaneous lymphomas are a distinct group of rare lymphoid neoplasms with absence of extracutaneous lymphomas at the time of presentation.
Ram Chandra Adhikari +3 more
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Primary cutaneous B-cell lymphoma and chronic leg ulcers in a patient with type 2 diabetes
The incidences of type 2 diabetes mellitus and many cancers are rapidly increasing worldwide. Diabetes is a strong risk factor for some cancers (including lymphomas) and is also associated with adverse cancer outcomes. After gastrointestinal tract, the
Alessandro Mantovani +10 more
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β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Cutaneous extranodal NK/T-cell lymphoma: a clinicopathologic study of 5 patients with array-based comparative genomic hybridization [PDF]
Extranodal natural killer/T-cell (ENK/T) lymphoma is a rare neoplasm, subcategorized into ENKITnasal ENK/T-N) and ENK/T-nasal type (ENK/T-NT) lymphomas.
E. Berti +7 more
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Primary cutaneous marginal-zone lymphoma [PDF]
Primary cutaneous B cell lymphomas (PCBCL) are thesecond most common type of primary cutaneouslymphoma. The three main types of PCBCL areprimary cutaneous marginal-zone lymphoma(PCMZL), primary cutaneous follicle-centerlymphoma, and primary cutaneous ...
Farhadian, Joshua +3 more
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