Results 151 to 160 of about 50,110 (265)

High Level of Component C1q Binding Protein (C1QBP) is Associated With Poor Prognosis and Dysfunction of Mast Cells in Lung Adenocarcinoma

open access: yesCancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Component C1q binding protein (C1QBP) is known as an important regulator of mitochondrial plasticity and is involved in antitumor immune response in cancers. Nevertheless, its role in lung adenocarcinoma (LUAD) still remains largely unknown.
Wei Li   +9 more
wiley   +1 more source

Empirical PK/PD Model for Differentiating Intrinsic Dosing Rules by Therapeutic Indication With Relevance for HIV‐1 Latency Reversal

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1414-1426, November 2026.
Romidepsin (RMD), an FDA‐approved histone deacetylase inhibitor for treating cancer, demonstrates potent latency‐reversing activity in vitro but has yielded suboptimal outcomes in kick‐and‐kill HIV‐cure trials when administered as a 5 mg/m2 infusion.
Lauren A. R. Tompkins   +7 more
wiley   +1 more source

Immunomodulation in Cutaneous T Cell Lymphoma

open access: yesFrontiers in Oncology, 2019
Martina Ferranti   +3 more
doaj   +1 more source

Management of advanced mycosis fungoides and Sézary Syndrome: International Recommendations for systemic treatments and allogeneic hematopoietic cell transplantation from the European Hematology Association, the EORTC Cutaneous Lymphoma Tumours Group, the International Society for Cutaneous Lymphoma, and the Lymphoma Working Party of the EBMT

open access: yesHemaSphere, Volume 10, Issue 11, November 2026.
Abstract Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...
Francesco Onida   +29 more
wiley   +1 more source

Liquid biopsy for molecular profiling in cutaneous T-cell lymphoma: a pilot feasibility study. [PDF]

open access: yesBlood Neoplasia
Sacknovitz Y   +8 more
europepmc   +1 more source

Molecular Tumor Boards in Malignant Melanoma: Uncovering Challenges and Opportunities in a Bicenter Retrospective Analysis in Germany

open access: yesInternational Journal of Cancer, Volume 159, Issue 9, Page 2290-2299, 1 November 2026.
Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel   +26 more
wiley   +1 more source

MEF2A Promotes Keratinocyte Proliferation and Migration Under High‐Glucose Conditions via Activation of the PI3K/AKT Signaling Pathway: Implications for Diabetic Wound Healing

open access: yesThe Journal of Gene Medicine, Volume 28, Issue 11, November 2026.
MEF2A promotes keratinocyte function in diabetic wound healing by activating the PI3K/AKT signaling pathway. In vivo studies revealed an upregulation of MEF2A expression in the skin wound tissues of diabetic mouse models. In vitro functional experiments confirmed that under high‐glucose conditions, MEF2A overexpression activates the PI3K/AKT signaling ...
Yuan Xue   +6 more
wiley   +1 more source

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