Results 191 to 200 of about 50,110 (265)

A Case of Cutaneous T-cell Lymphoma: The Importance of a Dermatology Consultation. [PDF]

Cureus
Tobar JA, Silva V, Tan V, Khalil K.
europepmc   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, Volume 183, Issue 21, Page 6261-6290, November 2026.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Inducible Costimulator and Its Ligand Promote Proliferation and Migration of Tumor Cells in Cutaneous T-Cell Lymphoma. [PDF]

Int J Mol Sci
Oka K, Miyagawa T, Morita H, Suga H, Miyagaki T, Shibata S, Kamijo H, Mizuno Y, Hisamoto T, Omori I, Boki H, Oka T, Takahashi-Shishido N, Sugaya M, Sato S.   +14 more
europepmc   +1 more source

New Treatment Strategy and Future Research Direction for BRAF‐Mutated Cancer

Cancer Science, Volume 117, Issue 11, Page 2901-2909, November 2026.
Treatment with BRAF inhibitor plus MEK inhibitor is currently used in BRAF‐mutated various malignancies except colorectal cancer, and treatments with BRAF and/or MEK inhibitors and anti‐EGFR antibody are used in BRAF‐mutated colorectal cancer. Despite recent advances in BRAF‐targeted therapies, their efficacy is still limited.
Masanobu Takahashi, Sakura Hiraide Taniguchi, Yuya Yoshida   +2 more
wiley   +1 more source

NF-κB Is a Potential Therapeutic Target for Histone Deacetylase Inhibitor-Resistant Cutaneous T-Cell Lymphoma. [PDF]

Cancer Sci
Takahashi Y, Kitadate A, Iwama S, Kuroki W, Abe K, Yamada M, Ikeda S, Tagawa H, Wakui H, Hikida M, Takahashi N.   +10 more
europepmc   +1 more source

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

Journal of Cutaneous Pathology, Volume 53, Issue 11, Page 994-999, November 2026.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil, Hozaifa Elameen, Ahmed K. Alomari   +2 more
wiley   +1 more source

IQDMA disrupts STAT5 nuclear transport through CDC42-PAK2 axis collapse in cutaneous T-cell lymphoma. [PDF]

Front Immunol
Dey S, Sorger H, Schlederer M, Perchthaler I, Metzelder M, Kenner L, Moriggl R, Wolf P.   +7 more
europepmc   +1 more source

Elevated lymphoma risk in patients with chronic pruritus and chronic prurigo

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 11, Page 1588-1596, November 2026.
Summary Background and objectives Chronic pruritus (CP) and chronic prurigo (CPG, including prurigo nodularis) are prevalent, debilitating diseases with diverse comorbidities, including malignancies. This retrospective cohort study evaluated the prevalence and risk of lymphoma in CP and CPG patients, including key risk factors, and sex‐ and ancestry ...
Svenja Royeck, Henning Olbrich, Steffen Koschmieder, Claudia Zeidler, Felix Witte, Konstantin Agelopoulos, Henning Wiegmann, Michael Storck, Johannes Benedict Oehm, Ralf J. Ludwig, Sonja Ständer   +10 more
wiley   +1 more source

Non-<i>JAK</i>-family gene fusions in cutaneous T-cell lymphoma highlights genetic diversity and potential therapeutic targets. [PDF]

Haematologica
Stuver R, Tang H, Dogan A, Epstein-Peterson ZD, Geller S, Ghione P, Johnson WT, Moskowitz A, Moy A, Virgen CA, Horwitz SM, Pulitzer M.   +11 more
europepmc   +1 more source

Brentuximab vedotin and radiotherapy for CD30-positive cutaneous T-cell lymphoma - a retrospective multicenter analysis. [PDF]

J Dtsch Dermatol Ges
Schummer P, Glatzel C, Schrüfer P, Lawrenz I, Dobos G, Wehkamp U, Hüning S, Stranzenbach R, Nicolay JP, Goebeler M, Wobser M.   +10 more
europepmc   +1 more source