Results 291 to 300 of about 84,355 (327)

Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets

MedComm, Volume 6, Issue 7, July 2025.
This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song, Hantian Liang, Fang Nan, Wenjing Chen, Junyao Li, Liu He, Yiping Cun, Zhenhong Li, Wei Zhang, Dunfang Zhang   +9 more
wiley   +1 more source

Sjögren's Syndrome: Epidemiology, Classification Criteria, Molecular Pathogenesis, Diagnosis, and Treatment

MedComm, Volume 6, Issue 7, July 2025.
A brief view of possible etiologic events preceding the diagnosis of desiccation syndrome. ABSTRACT Sjögren's syndrome (SS) is a chronic autoimmune disorder characterized by T‐cell‐mediated B‐cell hyperactivity and cytokine production, clinically manifesting, dry mouth and eyes, accompanied by pain and fatigue.
Ying Hu, Bin Wen, Yunfei Zhang, Xiaocui Wang, Xuemei Duan, Haonan Li, Yufeng Fan, Huifeng Shang, Yukai Jing   +8 more
wiley   +1 more source

The skin microbiome stratifies patients with cutaneous T cell lymphoma and determines event-free survival. [PDF]

NPJ Biofilms Microbiomes
Licht P, Dominelli N, Kleemann J, Pastore S, Müller ES, Haist M, Hartmann KS, Stege H, Bros M, Meissner M, Grabbe S, Heermann R, Mailänder V.   +12 more
europepmc   +1 more source

Cutaneous T cell lymphoma atlas reveals malignant T_H2 cells supported by a B cell-rich tumor microenvironment. [PDF]

Nat Immunol
Li R, Strobl J, Poyner EFM, Balbaa A, Torabi F, Mazin PV, Chipampe NJ, Stephenson E, Ramírez-Suástegi C, Shanmugiah VBM, Gardner L, Olabi B, Coulthard R, Botting RA, Zila N, Prigmore E, Gopee NH, Chroscik MA, Kritikaki E, Engelbert J, Goh I, Chan HM, Johnson HF, Ellis J, Rowe V, Tun W, Reynolds G, Yang D, Foster AR, Gambardella L, Winheim E, Admane C, Rumney B, Steele L, Jardine L, Nenonen J, Pickard K, Lumley J, Hampton P, Hu S, Liu F, Liu X, Horsfall D, Basurto-Lozada D, Grimble L, Bacon CM, Weatherhead SC, Brauner H, Wang Y, Bai F, Reynolds NJ, Allen JE, Jonak C, Brunner PM, Teichmann SA, Haniffa M.   +55 more
europepmc   +1 more source

How to treat primary cutaneous B cell lymphoma – Results from a monocentric cohort study on 98 patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 7, Page 822-830, July 2025.
Summary Background Primary cutaneous B cell lymphomas (CBCL) are chronic diseases with frequent relapses. Time to next treatment (TTNT) is an endpoint reflecting clinical benefit of treatments including patient perspectives. The objectives were to evaluate clinical characteristics, survival, prognosis and TTNT in CBCL.
Rohat Cankaya, Pit Leonard Kleiner, Franz Joachim Hilke, Rose Moritz, Thomas Eigentler, Max Schlaak, Gabor Dobos   +6 more
wiley   +1 more source

Cutaneous T-cell lymphoma in a JAK inhibitor patient: A case report. [PDF]

SAGE Open Med Case Rep
Mo S, Friedmann D.
europepmc   +1 more source

Editorial: The underlying pathophysiology and therapeutic approaches for cutaneous T-cell lymphoma. [PDF]

Front Immunol
Fuschiotti P.
europepmc   +1 more source

Role of IL-4 and IL-13 in Cutaneous T Cell Lymphoma. [PDF]

Life (Basel)
Mazzetto R, Miceli P, Tartaglia J, Ciolfi C, Sernicola A, Alaibac M.   +5 more
europepmc   +1 more source

Health-related quality of life in cutaneous T-cell lymphoma: A post hoc analysis of a phase 3 trial in mycosis fungoides and Sézary syndrome. [PDF]

J Eur Acad Dermatol Venereol
Ortiz Romero PL, Kim YH, Molloy K, Quaglino P, Scarisbrick J, Thornton S, Sandilands K, Dent JE, Nixon A, Williams A, Shinohara MM.   +10 more
europepmc   +1 more source

The Role of Surgery to Relieve Symptomatic Cutaneous T-Cell Lymphoma Refractory to Medical Treatments. [PDF]

Case Rep Oncol Med
Zhang WQ, Hecox EE, Dogar S, Walker ME.
europepmc   +1 more source