Results 41 to 50 of about 85,660 (309)

Non-mycosis fungoides cutaneous lymphomas in a referral center in Taiwan: A retrospective case series and literature review.

PLoS ONE, 2020
BACKGROUND:While mycosis fungoides (MF) and Sézary syndrome (SS) are the most common cutaneous lymphomas (CLs), there is limited data about non-MF/SS CLs. OBJECTIVE:We aimed to evaluate clinical characteristics of non-MF/SS CLs.
Kwei-Lan Liu, Wen-Chien Tsai, Chih-Hung Lee   +2 more
doaj   +1 more source

Plantar keratoderma of Sézary syndrome [PDF]

, 2017
Sézary syndrome is an extremely rare form of cutaneous T-cell lymphoma. It presents suddenly and is associated with a poor prognosis. Clinical recognition is crucial for the diagnostic process and initiation of appropriate treatment.
Fragkos, KC
core   +1 more source

Cutaneous Lymphoma in a Tertiary Skin Hospital and Referral Centre in Nepal

Journal of Nepal Health Research Council
Background: Primary cutaneous lymphomas are a distinct group of rare lymphoid neoplasms with absence of extracutaneous lymphomas at the time of presentation.
Ram Chandra Adhikari, Mahesh Shah, Werner Kempf, Anil Kumar Jha   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Update on primary cutaneous T-cell lymphomas rare subtypes

Dermatology Reports
Rare subtypes of cutaneous T-cell lymphomas (CTCL) include four entities, primary cutaneous γδ T-cell lymphoma, primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma, and primary cutaneous CD4+ small/medium T-cell ...
Silvia Alberti-Violetti, Emilio Berti
doaj   +1 more source

Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case

Лечащий Врач, 2021
The diagnosis of primary cutaneous CD4+ pleomorphic T-cell lymphoma of the skin from small and medium-sized cells is difficult due to the rare occurrence of this nosology.
N. V. Zilberberg, M. M. Kokhan, G. D. Safonova, O. G. Rimar, I. A. Kuklin, V. A. Iglikov   +5 more
doaj   +1 more source

Molluscum contagiosum infection with features of primary cutaneous anaplastic large cell lymphoma [PDF]

, 2019
CD30+ T cell pseudolymphomas (CD30+ PSL) are a group of benign inflammatory cutaneous disorders that can develop in settings of viral infections or drug reactions.
Lee, Jason B, Nikbakht, Neda, Ringe, John, Shalabi, Doaa   +3 more
core   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Transcript-indexed ATAC-seq for precision immune profiling. [PDF]

, 2018
T cells create vast amounts of diversity in the genes that encode their T cell receptors (TCRs), which enables individual clones to recognize specific peptide-major histocompatibility complex (MHC) ligands. Here we combined sequencing of the TCR-encoding
Buenrostro, Jason D, Chang, Howard Y, Corces, M Ryan, Davis, Mark M, Gennert, David G, Granja, Jeffrey M, Greenleaf, William J, Khavari, Paul A, Khodadoust, Michael S, Kim, Youn H, Lareau, Caleb A, Li, Rui, Mumbach, Maxwell R, Parker, Kevin R, Qi, Yanyan, Rubin, Adam J, Saligrama, Naresha, Satpathy, Ansuman T, Schep, Alicia N, Serratelli, William S, Wei, Yuning, Wu, Beijing   +21 more
core   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source