Results 1 to 10 of about 6,176 (146)

Intervertebral disc puncture predisposes the disc to Cutibacterium acnes infection via hematogenous and contiguous routes: a rat model study [PDF]

Journal of Orthopaedic Surgery and Research
Background Intervertebral disc degeneration (IVDD) is a primary cause of chronic low back pain. Recent evidence suggests a potential association between low-virulence infections, particularly by Cutibacterium acnes, and IVDD.
Yuchao Jia, Shengbo Huang, Tianyi Li, Baoshan Xu   +3 more
doaj   +2 more sources

The Effect of Myrtacine and Celastrol-Enriched Extract on Cutibacterium acnes Extracellular Vesicles. [PDF]

Int J Dermatol
Myrtacine alone, Celastrol‐enriched extract alone, or the combination of both ingredients were added to the culture medium either before (preventive condition) or after (modulating condition) incubation with C. acnes IA1 extracellular vesicles (EVs) from healthy and acne skin in immortalized keratinocytes (HaCaT cells) and human skin explants.
Cheung CT, Mias C, Lancien U, Corvec S, Mengeaud V, Khammari A, Duplan H, Dréno B.   +7 more
europepmc   +2 more sources

Intradiscal <i>Cutibacterium acnes</i> Sustains Modic Type 1-Like Lesions Over Time in a Rat Lumbar Endplate Injury Model. [PDF]

JOR Spine
Intradiscal C. acnes injection sustained MC1‐like lesions with persistent neutrophil sustenance in an etiology‐specific lumbar MC rat model. This suggests that patients with bacterial MC etiology may persist in painful MC1, highlighting C. acnes and neutrophils as potential targets to promote MC1‐to‐MC2 conversion and improve pain and disability ...
Heggli I, Lai A, Iliff D, Burkhard MD, Koehne N, Singh H, Huang JJ, Seifert AC, Laudier D, Bonnheim N, Rodriguez L, Jacobsen TD, Iatridis JC.   +12 more
europepmc   +2 more sources

Phytochemicals, promising strategies combating Cutibacterium acnes [PDF]

Frontiers in Pharmacology
The excessive proliferation of Cutibacterium acnes (C. acnes) is an important reason for the occurrence of acne vulgaris, and genetic detection ratio of C. acnes in acne is as high as 60.5%. Until now, the treatment of C.
Cuilian Sun, Yuhang Na, Ziyu Wang, Tingting Zhu, Xiaojuan Liu   +4 more
doaj   +2 more sources

Post-cranial Neurosurgery Cutibacterium acnes Infections: Clinical Correlates, Presentation, and Outcomes—A Matched Case–Case–Control Study [PDF]

Infectious Diseases and Therapy
Introduction Although Cutibacterium acnes is considered a typical pathogen of postoperative central nervous system (CNS) infections, data on its role as a pathogen, remain limited. This study aimed to address this knowledge gap.
Neta Shirin, Ofek Arviv, Karina Zinman, Bar Mizrahi, Yovel Peretz, Sarit Moshayev Revale, Idan Levitan, Elena Mishuk, Lior Ungar, Asaf Biber, Sharon Amit, Tal Zilberman-Daniels, Zvi R. Cohen, Dafna Yahav, Ili Margalit   +14 more
doaj   +2 more sources

 De novo design of pimarane diterpenoid compounds as potential alternatives to sarecycline for acne vulgaris treatment [PDF]

Pharmacia, 2023
Acne vulgaris is a prevalent skin disorder that affects both adolescents and adults and has a major psychological impact. Antibiotic resistance is one issue that current therapies, including antibiotics, must address.
Adeola Tawakalitu Kola-Mustapha
doaj   +3 more sources

Periprosthetic hip infections in a Swedish regional hospital between 2012 and 2018: is there a relationship between Cutibacterium acnes infections and uncemented prostheses? [PDF]

Journal of Bone and Joint Infection, 2021
The purpose of this study was to evaluate patients requiring in-patient care due to a periprosthetic joint infection (PJI), with respect to bacterial agents, surgical treatment, antibiotics, and outcome.
U. Hedlundh, M. Zacharatos, J. Magnusson, M. Gottlander, J. Karlsson, J. Karlsson   +5 more
doaj   +1 more source

Complete Draft Genome Sequence of Cutibacterium (Propionibacterium) acnes Type Strain ATCC6919

International Journal of Dermatology and Venerology, 2020
. Objectives:. The wide use of antibiotics for acne is the main cause of drug-resistant Cutibacterium acnes. However, the complete genetic sequence reference of C. acnes has not yet been reported.
Hui-Jing Tang, Kai-Wei Si, Xiao Zhang, He-Ling Zhu, Wen-Liang Zheng, Xi-Bao Zhang, Jing-Yao Liang, Jian-Bo Ruan   +7 more
doaj   +1 more source

Detection of Cutibacterium acnes from multiple miliary osteoma cutis

Clinical Case Reports, 2022
The patient had a history of acne vulgaris at a young age. The excisional biopsy from the nodule of the face showed the findings of multiple miliary osteoma cutis (MMOC).
Makoto Kondo, Keiichi Yamanaka
doaj   +1 more source

Shotgun metagenomic sequencing reveals skin microbial variability from different facial sites

Frontiers in Microbiology, 2022
Biogeography (body site) is known to be one of the main factors influencing the composition of the skin microbial community. However, site-associated microbial variability at a fine-scale level was not well-characterized since there was a lack of high ...
Qingzhen Wei, Qingzhen Wei, Zhiming Li, Zhenglong Gu, Xiao Liu, Jean Krutmann, Jiucun Wang, Jiucun Wang, Jiucun Wang, Jingjing Xia, Jingjing Xia   +10 more
doaj   +1 more source