Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Reducing unintended valgus deformity after supracondylar femoral derotational osteotomy: Influence of derotation amount and osteotomy method based on femoral antecurvature. [PDF]
Park J +5 more
europepmc +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
A level set-based process planning method for the additive and subtractive hybrid manufacturing of a flow channel with an inner cavity. [PDF]
Li L +7 more
europepmc +1 more source
Smooth Ranking SVM via Cutting-Plane Method
The most popular classification algorithms are designed to maximize classification accuracy during training. However, this strategy may fail in the presence of class imbalance since it is possible to train models with high accuracy by overfitting to the majority class. On the other hand, the Area Under the Curve (AUC) is a widely used metric to compare
Ozcan, Erhan Can +3 more
openaire +1 more source
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
Research on Multi-Sensor Data Fusion Based Real-Scene 3D Reconstruction and Digital Twin Visualization Methodology for Coal Mine Tunnels. [PDF]
Zhu H, Jin J, Zhao S.
europepmc +1 more source
Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih +40 more
wiley +1 more source
An Intelligent Joint Identification Method and Calculation of Joint Attitudes in Underground Mines Based on Smartphone Image Acquisition. [PDF]
Li G, Zhu J, Jin C, Mao X, Wang Q.
europepmc +1 more source

