Results 121 to 130 of about 1,418,495 (362)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
EXPERIMENTAL STUDY ON CUTTING ENERGY CONSUMPTION OF COAL MINING UNDER DIFFERENT WORKING CONDITIONS
Jixie qiangdu, 2019 In order to study the cutting energy consumption characteristics of coal miner under complicated conditions, the MG500/1180-WD shearer was cut out under different working conditions by collecting the cutting energy consumption model of coal mining ...
HAO ZhiYong +3 more
doaj
工程科学学报, 2017 Cutting energy can be transformed into cutting heat, which directly affects the cutting temperature. Therefore, it is important to understand the generation, transfer, and transformation of cutting energy to cutting temperature.
ZHAN Gang +3 more
doaj +1 more source
Characterization of Si and SiO2 in Dust Emitted during Granite Polishing as a Function of Cutting Conditions. [PDF]
Materials (Basel), 2022 Kouam J +3 more
europepmc +1 more source
Effects of cutting frequency on plant production, N-uptake and N2 fixation in harvested and below-harvest plant biomass of grass clover [PDF]
, 2006 Nitrogen (N) accumulating in stubble, stolons and roots is an important component in N balances in perennial ryegrass-white clover swards, and the effects of cutting frequency on the biomass of above- and below-harvest height were studied during two ...
Vinther, F.P.
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Optimization and Sensitivity Analysis of the Cutting Conditions in Rough, Semi-Finish and Finish Honing. [PDF]
Materials (Basel), 2021 Buj-Corral I +2 more
europepmc +1 more source
Korean Journal of Horticultural Science and Technology, 2012 This study was carried out to examine the effect of cutting condition on the growth of rooted cuttings and their subsequent growth of cut flower in plug cutting of Dendranthema grandiflorum 'Baekma'. The more leaves were attached to the cutting, the higher shoot growth of rooted cutting was observed.
Yong-Kweon Yoo, Yong-Seung Roh
openaire +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source