Results 111 to 120 of about 385,035 (296)

A review of micro-resolved crystochemical and mechanical probes for sustainable cement-based material studies

npj Materials Sustainability
Exploring sustainable alternative constituents is a key pathway to carbon-neutralization of concrete, but often limited to insufficient understandings of how they interact with conventional concrete components at microscale. In this paper we reviewed the
Zhe Zhang, Yu Yan, Guoqing Geng
doaj   +1 more source

Machining of Nickel Alloy by Cutting Tool with Prepared Cutting Edge preparation [PDF]

METAL Conference Proeedings, 2019
Tomáš ZLÁMAL, Šárka MALOTOVÁ, Tomáš SZOTKOWSKI, Ondřej VORTEL, Antonín TREFIL   +4 more
openaire   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Integrating Emerging Areas of Nursing Science into PhD Programs [PDF]

, 2015
The Council for the Advancement of Nursing Science aims to “facilitate and recognize life-long nursing science career development” as an important part of its mission.
Conley, Yvette P., Dunbar-Jacob, Jacqueline, Heitkemper, Margaret M., Henly, Susan J., McCarthy, Ann Marie, McCarthy, Donna O., Moore, Shirley M., Redeker, Nancy S., Stone, Patricia W., Titler, Marita, Wyman, Jean F.   +10 more
core   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Ethosomes: A Promising Drug Delivery Platform for Transdermal Application

Chemistry
In recent years, transdermal drug delivery systems have gained considerable attention for their ability to enhance patient compliance and provide consistent drug release.
Bo Zhan, Jiawen Wang, Hongyu Li, Kexin Xiao, Xiaohua Fang, Yajun Shi, Yanyan Jia   +6 more
doaj   +1 more source

Tool Life of PM-HSS Cutting Tools when Milling of Titanium Alloy [PDF]

, 2017
Machining of titanium alloys meets with poor life of a cutting tool. It is caused by a low thermal conductivity and by a high strength-to-weight ratio of the alloys. Various approaches for cost-effective and productive machining titanium alloys are still
Bach P., Trmal G., Zeman P.
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source