Results 71 to 80 of about 385,035 (296)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Experimental investigation to assess the effects of trumpet hone on tool life and surface quality in milling of AISI4140 steel [PDF]
FME Transactions, 2019 Cutting edge preparation is proven to improve the tool life by avoiding sudden failures. Honed edge is effective in stabilizing the tool but has an adverse effect on surface quality.
Shiva Pradeep N. +2 more
doaj
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
The structure and possible origins of stacking faults in gamma-yttrium disilicate [PDF]
, 2009 Parallel stacking faults on (010) planes are frequently observed in hot-pressed Y2Si2O7. A combination of conventional dark-field imaging and high-resolution transmission electron microscopy was used to investigate the structure of these faults and it ...
Batalieva NG +5 more
core +3 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Suppression of tool wear by extremely short-duration cutting
Mechanical Engineering Journal, 2015 High-speed cutting has various advantages such as high material removal rates and reduction of machining time. However, the greatest problem of high-speed cutting is its excessive tool wear rate.
Yuki TERASAKA +3 more
doaj +1 more source
Structural and torsional properties of the Trachycarpus fortunei palm petiole [PDF]
, 2006 The Trachycarpus fortunei palm is a good example of a palm with a large leaf blade supported by a correspondingly large petiole. The way in which the material and functional properties of the petiole interact is analysed using engineering and botanical ...
Atherton, MA +3 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Engineering Science and Technology, an International JournalThe machining of slots in aeronautical turbine cases and discs is an extremely delicate operation. First, these parts require materials with excellent wear, high temperature and corrosion properties, such as the low machinability materials of the S group.
Pablo Fernández-Lucio +3 more
doaj +1 more source
Experimental and numerical analysis of micromechanical damage in the punching process for High-Strength Low-Alloy steels [PDF]
, 2014 Sequential sheet metal forming processes can result in the accumulation of work hardening and damage effects in the workpiece material. The mechanical strength of the final component depends on the “evolution” of these two characteristics in the ...
ACHOURI, Mohamed +3 more
core +3 more sources