Results 61 to 70 of about 12,050 (256)

Monitoring of Burr and Prefailure Phase Caused by Tool Wear in Micro-Drilling Operations Using Thrust Force Signals

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
The purpose of this study is to investigate the effectiveness of thrust force signals for estimation of the burr occurring at the outlet of a drilled hole and the prefailure phase caused by tool wear in drilling holes through thin stainless steel plate ...
Eiji KONDO, Ryoga KAMO, Hiroshi MURAKAMI
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Analysis of S.S.43100 by Turning of Ti16Zr PVD Coated Tool Inserts and Optimization of Surface Roughness Using Taguchi Method

open access: yesITEGAM-JETIA
 The performance of PVD coated carbide inserts for various machinability aspects during machining of hardened alloy steel AISI 43100, under a dry cutting environment.
Nishadevi N. jadeja   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Turn+: A MATLAB-based software for dynamic turning, chatter analysis, and surface roughness prediction

open access: yesSoftwareX
Turning and boring processes are widely used to machine shafts, tubes, casings, and rings across sectors from automotive to aerospace, yet productivity is often limited by regenerative chatter, which couples cutting mechanics with tool–workpiece dynamics,
Gorka Urbikain-Pelayo   +3 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Energy-Based Analysis of Ultrasonically Assisted Turning

open access: yesShock and Vibration, 2011
The process of ultrasonically-assisted turning (UAT) is a superposition of vibration of a cutting tool on its standard movement in conventional turning (CT).
G.A. Volkov   +5 more
doaj   +1 more source

A proposition for machining error estimation based on geometric analysis of ball end milling

open access: yesNihon Kikai Gakkai ronbunshu, 2017
The ball end mill is used as a tool for cutting the metal mold and some complicated shape lake a screw. The demand for the precise machining of the ball end milling is increasing. The ball end milling has the unavoidable problem of machining error by the
Hisanobu TERAI   +3 more
doaj   +1 more source

Cutting Force Estimation Systems Based on AC Spindle Drive.

open access: yesJSME International Journal Series C, 2000
Monitoring of the cutting force signals in turning process has been well emphasized for unmanned machining. Although the cutting force can be directly measured by a tool dynamometer, direct sensing in factory environment is not feasible because of high cost and limitations in setup.
HUH, Kunsoo, LEE, Kang-Kyu
openaire   +2 more sources

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