Results 91 to 100 of about 837,325 (362)

A Cutting-plane Method for Semidefinite Programming with Potential Applications on Noisy Quantum Devices [PDF]

, 2021
Jakub Mareček, Albert Akhriev
openalex   +1 more source

An exact cutting plane method for the Euclidean max-sum diversity problem

European Journal of Operational Research, 2023
Sandy Spiers, H. T. Bui, R. Loxton
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Minimizing airtime by optimizing tool path in computer numerical control machine tools with application of A* and genetic algorithms

Advances in Mechanical Engineering, 2017
Research on tool path planning has been limited to minimize airtime by optimizing tool travel path in one machining plane without obstacles. To address this limitation, a method for tool path optimization that exploits A* and genetic algorithms to find ...
Naveen Senniappan Karuppusamy, Bo-Yeong Kang   +1 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Nonlinear Dynamic Analysis of the Cutting Process of a Nonextensible Composite Boring Bar

Shock and Vibration, 2020
A nonlinear dynamic analysis of the cutting process of a nonextensible composite cutting bar is presented. The cutting bar is simplified as a cantilever with plane bending.
Bole Ma, Yongsheng Ren
doaj   +1 more source

Strain Rate of Metal Deformation in the Machining Process from a Fluid Flow Perspective

Applied Sciences, 2020
Metal cutting speeds are getting faster with the development of high-speed cutting technology, and with the increase in cutting speed, the strain rate will become larger, which makes the study of the metal cutting process more inconvenient.
Keguo Zhang, Keyi Wang, Zhanqiang Liu, Xiaodong Xu   +3 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Displacements analysis of self-excited vibrations in turning

, 2009
The actual research deals with determining by a new protocol the necessary parameters considering a three-dimensional model to simulate in a realistic way the turning process on machine tool.
A Cowley, A Moufki, Alain Gérard, AV Dassanayake, C Mei, CF Bisu, CK Chen, Claudiu F. Bisu, DA Axinte, DE Dimla Sr, HE Merrit, I Marinescu, IN Tansel, JD Calderon-Najera, Jean-Yves K’nevez, K Liu, LZ Qiang, M Thomas, O Cahuc, O Cahuc, PG Benardos, Philippe Darnis, RL Kegg, W Grzeski, X Li, Y Sahin, YS Chiou   +26 more
core   +1 more source