Results 101 to 110 of about 904,011 (327)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A Theoretical Study on the use of Passive Soil Resistance in Winch Anchor Design [PDF]
, 1983 This paper describes work being carried out to determine the length and depth of a cutting blade required to support a rescue vehicle fitted with a winch. Analytical work described relates mostly to the suitability of blade used.
Ahmad, Desa
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Discrete Dynamics in Nature and Society, 2012 This paper presents a 2D convergence density criterion for minimizing the total junction delay at isolated junctions in the lane-based optimization framework.
C. K. Wong, Y. Y. Lee
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Solving Variational Inequalities Defined on A Domain with Infinitely Many Linear Constraints [PDF]
, 2002 We study a variational inequality problem whose domain is defined by infinitely many linear inequalities. A discretization method and an analytic center based inexact cutting plane method are proposed. Under proper assumptions, the convergence results
Birbil, S.I. (Ilker) +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Partial Differential Equations for 3D Data Compression and Reconstruction [PDF]
This paper describes a PDE-based method for 3D reconstruction of surface patches. The PDE method is exploited using data obtained from standard 3D scanners.
Osman, Abdusslam +2 more
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Abstract and Applied Analysis, 2014 Under the condition that the values of the objective function and its subgradient are computed approximately, we introduce a cutting plane and level bundle method for minimizing nonsmooth nonconvex functions by combining cutting plane method with the ...
Jie Shen, Dan Li, Li-Ping Pang
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Jixie chuandong, 2021 Traditional small module spiral bevel gear milling needs to use a large number of cutting fluid，which will not only cause environmental pollution，but also increase production costs，the new technology of high speed dry cutting does not use cutting fluid ...
Qi Liu, Hua Zhang, Jianjun Yang
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