Results 111 to 120 of about 837,325 (362)

Solving Variational Inequalities Defined on A Domain with Infinitely Many Linear Constraints [PDF]

, 2002
We study a variational inequality problem whose domain is defined by infinitely many linear inequalities. A discretization method and an analytic center based inexact cutting plane method are proposed. Under proper assumptions, the convergence results
Birbil, S.I. (Ilker), Fang, S-C. (Shu-Cherng), Wu, S.   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Partial Differential Equations for 3D Data Compression and Reconstruction [PDF]

This paper describes a PDE-based method for 3D reconstruction of surface patches. The PDE method is exploited using data obtained from standard 3D scanners.
Osman, Abdusslam, Robinson, Alan, Rodrigues, Marcos   +2 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

A Cutting Plane and Level Stabilization Bundle Method with Inexact Data for Minimizing Nonsmooth Nonconvex Functions

Abstract and Applied Analysis, 2014
Under the condition that the values of the objective function and its subgradient are computed approximately, we introduce a cutting plane and level bundle method for minimizing nonsmooth nonconvex functions by combining cutting plane method with the ...
Jie Shen, Dan Li, Li-Ping Pang
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Research on High Speed Dry Cutting Technology and Machining Experiment of Small Module Spiral Bevel Gear

Jixie chuandong, 2021
Traditional small module spiral bevel gear milling needs to use a large number of cutting fluid，which will not only cause environmental pollution，but also increase production costs，the new technology of high speed dry cutting does not use cutting fluid ...
Qi Liu, Hua Zhang, Jianjun Yang
doaj  

MR histological correlation: A method for cutting specimens along the imaging plane in animal or ex vivo experiments [PDF]

, 2005
Olivier Rouvière, Carol Reynolds, Thomas C. Hulshizer, Phillip J. Rossman, Yuan Le, Joel P. Felmlee, Richard L. Ehman   +6 more
openalex   +1 more source

An Analytic Center Cutting Plane Method to Determine Complete Positivity\n of a Matrix [PDF]

, 2020
Riley Badenbroek, Etienne de Klerk
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source