Results 131 to 140 of about 837,325 (362)
An exact cutting plane method for solving p-dispersion-sum problems [PDF]
, 2022 Sandy Spiers, Hòa T. Bùi, Ryan Loxton
openalex +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
An ILP Solver for Multi-label MRFs with Connectivity Constraints
, 2017 Integer Linear Programming (ILP) formulations of Markov random fields (MRFs) models with global connectivity priors were investigated previously in computer vision, e.g., \cite{globalinter,globalconn}.
Ayed, Ismail Ben +5 more
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Study on diffractive optical characteristics and elimination methods of diamond fly-cutting optical plane [PDF]
, 2023 Yawen Guo +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Jixie chuandong, 2009 An arc in the plane that is tangent with the base cone of the spiral bevel gear,and absolutely rolling on the cone surface will form the surface of a spiral bevel bear with spherical involutes tooth form,a new precisely cutting way of the spiral bevel ...
张学成, 李春光, 李桂娇
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
A cutting-plane method with internal iteration points for the general convex programming problem
Учёные записки Казанского университета: Серия Физико-математические наукиA cutting method for solving the problem of convex programming was proposed. The method calculates iteration points based on approximation by polyhedral sets of the constraint region and the epigraph of the objective function.
I. Ya. Zabotin +2 more
doaj +1 more source