Results 51 to 60 of about 904,011 (327)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

PENERAPAN BRANCH AND BOUND ALGORITHM DALAM OPTIMALISASI PRODUKSI ROTI

E-Jurnal Matematika, 2016
Companies which engaged in production activities such as Ramadhan Bakery would want optimal profit in their every production. The aim of this study was to find optimal profit and optimal combination of bread production (original chocolate bread, extra ...
GEDE SURYAWAN, NI KETUT TARI TASTRAWATI, KARTIKA SARI   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A cutting plane method based on redundant rows for improving fractional distance [PDF]

2008 5th International Symposium on Turbo Codes and Related Topics, 2008
In this paper, an idea of the cutting plane method is employed to improve the fractional distance of a given binary parity check matrix. The fractional distance is the minimum weight (with respect to lscr1-distance) of vertices of the fundamental ...
M. Miwa, T. Wadayama, I. Takumi
semanticscholar   +1 more source

Finding an optimal seating arrangement for employees

Croatian Operational Research Review, 2015
The paper deals with modelling a specifc problem called the Optimal Seating Arrangement (OSA) as an Integer Linear Program and demonstrated that the problem can be efficiently solved by combining branch-and-bound and cutting plane methods.
Ninoslav Čerkez, Rebeka Čorić, Mateja Đumić, Domagoj Matijević   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Stabilized Benders methods for large-scale combinatorial optimization, with appllication to data privacy [PDF]

, 2017
The Cell Suppression Problem (CSP) is a challenging Mixed-Integer Linear Problem arising in statistical tabular data protection. Medium sized instances of CSP involve thousands of binary variables and million of continuous variables and constraints ...
Baena, Daniel, Castro Pérez, Jordi, Frangioni, Antonio   +2 more
core   +1 more source

Cutting-plane theory: Algebraic methods

Discrete Mathematics, 1978
AbstractThis paper is a survey, with new results, of the algebraic approach to cutting-planes. The new results are a subadditive dual program for integer programs, and a generalization of R. Gomory's linear inequality characterization of the cuts valid for the group problem.
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Cutting-plane methods witout nested approximating sets

, 2023
In connection with the needs of solving optimization problems, the development of conditional minimization methods with convenient numerical implementation continues to attract the attention of mathematicians. In this monograph we propose methods for solving mathematical programming problems that belong to the class of cutting methods.
Zabotin, Igor, Yarullin, Rashid
openaire   +2 more sources