Results 81 to 90 of about 904,011 (327)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
On-Machine Measurement of Cutting Tool Edge Profile by Detecting Fluorescence from Cutting Fluid
MATEC Web of Conferences, 2015 We propose a novel on-machine measurement method of the tool cutting edge profile by using cutting fluid adhered on the tool surface. In an environment of on-machine tool profile measurement, the profile is difficult to measure with the conventional ...
Maruno Kenji +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Call Center Staffing with Simulation and Cutting Plane Methods [PDF]
Annals of Operations Research, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Atlason, Júlíus +2 more
openaire +2 more sources
Acceleration of Lagrangian Method for the Vehicle Routing Problem with Time Windows
International Journal of Industrial Engineering and Production Research, 2012 The analytic center cutting plane method (ACCPM) is one of successful methods to solve nondifferentiable optimization problems. In this paper ACCPM is used for the first time in the vehicle routing problem with time windows (VRPTW) to accelerate ...
Hadi Karimi, Abbas Seifi
doaj
SensorsTo address the challenges posed by significant parallax, dynamic changes in monitoring camera positions, and the need for rapid wide-field image stitching in underground coal mine tunneling faces, this paper proposes a fast image stitching method for ...
Hongda Zhu, Sihai Zhao
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
On the Efficient Solution of Variational Inequalities; Complexity and Computational Efficiency [PDF]
, 2002 In this paper we combine ideas from cutting plane and interior point methods in order to solve variational inequality problems efficiently. In particular, we introduce a general framework that incorporates nonlinear as well as linear "smarter" cuts ...
Perakis, Georgia, Zaretsky, M. (Marina)
core
Advances in Mechanical Engineering, 2017 Research on tool path planning has been limited to minimize airtime by optimizing tool travel path in one machining plane without obstacles. To address this limitation, a method for tool path optimization that exploits A* and genetic algorithms to find ...
Naveen Senniappan Karuppusamy +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source