Results 181 to 190 of about 23,957 (296)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Assessing the accuracy of 3D assistive technologies for surgical guidance of osteosarcoma resections: a comparative laboratory study of mixed reality, patient-specific instruments and freehand approaches. [PDF]

Arthroplasty
Caceres-Alban J, Lindskog DM, Sieberer JM, Glennon A, Tommasini SM.   +4 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The effect of mixed fatigue on knee biomechanics and muscle activation during sidestep cutting in elite soccer players. [PDF]

BMC Sports Sci Med Rehabil
Chen K, Sun D, Chen D, Xuan B, Wang D, Song Y, Cen X, Jemni M, Fekete G, Gu Y.   +9 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Navigation-Assisted Bilateral Troughing Technique for Lumbar Laminectomy: A Stepwise Approach to Safe, Teachable, and Efficient Decompression. [PDF]

Cureus
Siddiqi I, Shay A, Ueno A, Dennison S, Wong C, Rao SC, Sweiss R, Miulli DE.   +7 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Real-time intraoperative motion-following robotic assistance improves efficiency and accuracy in total knee arthroplasty: a retrospective comparative study. [PDF]

Arthroplasty
Li Z, Xu Z, Li D, Shao H, Li H, Kong K, Zhai Z.   +6 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

3D reconstruction and etching profile simulation for wiggling active area effect in dynamic random access memory manufacturing. [PDF]

Commun Eng
Hu Z, Wen J, Yang C, Shao H, Zhai Y, Ge R, He X, Men Z, Yang Y, Sun D, Liu Z, Shang D, Li Z, Li J, Filipovic L, Chen R, Li L.   +16 more
europepmc   +1 more source