Results 61 to 70 of about 11,222 (260)

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

open access: yesAdvanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding   +7 more
wiley   +1 more source

Solving two dimensional non-guillotine cutting problem Using Particle Swarm Optimization [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2012
One of the solutions for solving cutting stock problem in differentindustries, such as sheet metal, lumber, glass, paper and textile, isapplying ,Particle Swarm Optimization to minimize the waste ofrawmaterials.
Faezeh Asadian Ardakani   +1 more
doaj  

Minimizing the total waste in the one-dimensional cutting stock problem with the African buffalo optimization algorithm. [PDF]

open access: yesPeerJ Comput Sci, 2023
Montiel-Arrieta LJ   +5 more
europepmc   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

open access: yesAdvanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen   +12 more
wiley   +1 more source

Metal Battery Anode: Rich in Electrons, Rich in Problems: A Critical Review from Industrial Perspectives

open access: yesAdvanced Science, EarlyView.
Metal‐anode batteries using Li, Na, Mg, and Ca offer exceptionally high energy density, but dendrites, unstable interphases, cracking, and pore formation hinder durability and safety. This review shows how careful electrolyte and interphase design can stabilize these reactive metals.
Jian Pan   +3 more
wiley   +1 more source

Single‐Atom‐Enhanced Fully Inkjet‐Printed Electrochemical Sensor for Dopamine Detection

open access: yesAdvanced Science, EarlyView.
Fully inkjet‐printed paper‐based dopamine sensors are fabricated using nitrogen‐doped graphene acid functionalized with copper single atoms. The copper sites uniquely enhance dopamine oxidation through strong molecular adsorption, as verified by electrochemical measurements and DFT calculations. The approach highlights the potential of single‐atom inks
Martin‐Alex Nalepa   +11 more
wiley   +1 more source

Modeling the combined problem of determining the lot sizing and cutting stock of raw materials and solving it using a combined method based on a genetic algorithm and an exact solution method [PDF]

open access: yesتصمیم گیری و تحقیق در عملیات
Purpose: The problem of determining the lot sizing and cutting stock raw materials are two important issues in the production industry, which are used in the production process of many industries, including furniture, paper, aluminum, metal industries ...
Ali Mohaghar   +3 more
doaj   +1 more source

In situ column generation for a cutting-stock problem [PDF]

open access: yesComputers & Operations Research, 2007
The paper deals with the development of a new model for the cutting stock problem (CSP). A bilinear programming model describes the CSP and a modification of it is proposed. Some patterns are fixed and the rest of the linear terms are linearized. A computational method is developed and some experiments are used for evaluating its behavior. Upper bounds
openaire   +2 more sources

Home - About - Disclaimer - Privacy