Results 181 to 190 of about 892,705 (358)
Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer+8 more
wiley +1 more source
Evaluation of Cutting-Tool Coating on the Surface Roughness and Hole Dimensional Tolerances during Drilling of Al6061-T651 Alloy. [PDF]
Al-Tameemi HA+6 more
europepmc +1 more source
MANUFACTURE OF HIGH SPEED STEEL CUTTING TOOL BY NEW METHOD OF DEPOSIT METAL AND ITS NATURE
Toshihiko Simomura, Tatsuro Kaida
openalex +2 more sources
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source
Analytical Study on Temperature Rise of a Cutting Tool by Electrical Method
明 山本
openalex +2 more sources
Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang+13 more
wiley +1 more source
The Failure Process of High Speed Steel Tools on the Cutting of Mild Steel
Keiji Okushima, Nobuji ASAKA
openalex +2 more sources
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran+5 more
wiley +1 more source
A study on the Roughness of Machined Surface of Metals : The Effect of Relief Angle of Cutting Tool
Keiji Okushima, Mutsuo Tanaka
openalex +2 more sources