Results 201 to 210 of about 867,518 (339)

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

From Powders to Performance-A Comprehensive Study of Two Advanced Cutting Tool Materials Sintered with Pressure Assisted Methods. [PDF]

Materials (Basel)
Momot K, Klimczyk P, Leszczyńska-Madej B, Podsiadło M, Rumiantseva Y, Gubernat A.   +5 more
europepmc   +1 more source

Flow along Tool-Chip Interface in Orthogonal Metal Cutting

, 1966
H. E. Enahoro, P.L.B. Oxley
openalex   +2 more sources

Robust integer optimization of turning parameters for cutting tool sustainability and machining economics in discrete production. [PDF]

Heliyon
Chung C, Andrianto A, Wang PC.
europepmc   +1 more source

Study on an Experimental Relationships between Machinability of Free-Cutting Steels and Normal Rake Angles of Various Cutting Tools

, 1962
Takeshi Ito
openalex   +2 more sources

Numerical Studies of Influencing Factors on the Homogeneity of the Powder Mixture during the Powder Spreading Process of Powder Bed Fusion–Laser Beam/Metal

Advanced Engineering Materials, EarlyView.
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng, Ziping Sang, Jiali Zhang, Felix Radtke, Louis Becker, Simone Herzog, Sebastian Weber, Christoph Broeckmann   +7 more
wiley   +1 more source

The Influence of the Binder Phase on the Properties of High-Pressure Sintered Diamond Polycrystals or Composites for Cutting Tool Applications. [PDF]

Materials (Basel)
Jaworska L.
europepmc   +1 more source

Deep Anomaly Detection for CNC Machine Cutting Tool Using Spindle Current Signals. [PDF]

Sensors (Basel), 2020
Li G, Fu Y, Chen D, Shi L, Zhou J.
europepmc   +1 more source

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

Advanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani, Aditi Singh, Behnam Ashrafi   +2 more
wiley   +1 more source

Effects of cutting tool geometry on material removal of a gradient nanograined CoCrNi medium entropy alloy. [PDF]

Beilstein J Nanotechnol
Lu YS, Hung YX, Bui TX, Fang TH.
europepmc   +1 more source